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Erythromycin breath test.
Rivory LP, Watkins PB. Rivory LP, et al. Among authors: watkins pb. Clin Pharmacol Ther. 2001 Oct;70(4):395-9. Clin Pharmacol Ther. 2001. PMID: 11673756 No abstract available.
Heterogeneity of CYP3A isoforms metabolizing erythromycin and cortisol.
Hunt CM, Watkins PB, Saenger P, Stave GM, Barlascini N, Watlington CO, Wright JT Jr, Guzelian PS. Hunt CM, et al. Among authors: watkins pb. Clin Pharmacol Ther. 1992 Jan;51(1):18-23. doi: 10.1038/clpt.1992.3. Clin Pharmacol Ther. 1992. PMID: 1732074
The erythromycin breath test as a predictor of cyclosporine blood levels.
Watkins PB, Hamilton TA, Annesley TM, Ellis CN, Kolars JC, Voorhees JJ. Watkins PB, et al. Clin Pharmacol Ther. 1990 Aug;48(2):120-9. doi: 10.1038/clpt.1990.126. Clin Pharmacol Ther. 1990. PMID: 2116259
Erythromycin breath test.
Watkins PB. Watkins PB. Clin Pharmacol Ther. 2000 May;67(5):577-8. doi: 10.1016/S0009-9236(01)90133-X. Clin Pharmacol Ther. 2000. PMID: 10824637 No abstract available.
Identification of a novel route of extraction of sirolimus in human small intestine: roles of metabolism and secretion.
Paine MF, Leung LY, Lim HK, Liao K, Oganesian A, Zhang MY, Thummel KE, Watkins PB. Paine MF, et al. Among authors: watkins pb. J Pharmacol Exp Ther. 2002 Apr;301(1):174-86. doi: 10.1124/jpet.301.1.174. J Pharmacol Exp Ther. 2002. PMID: 11907172
Hepatic but not intestinal CYP3A4 displays dose-dependent induction by efavirenz in humans.
Mouly S, Lown KS, Kornhauser D, Joseph JL, Fiske WD, Benedek IH, Watkins PB. Mouly S, et al. Among authors: watkins pb. Clin Pharmacol Ther. 2002 Jul;72(1):1-9. doi: 10.1067/mcp.2002.124519. Clin Pharmacol Ther. 2002. PMID: 12151999 Clinical Trial.
Is quinine a suitable probe to assess the hepatic drug-metabolizing enzyme CYP3A4?
Wanwimolruk S, Paine MF, Pusek SN, Watkins PB. Wanwimolruk S, et al. Among authors: watkins pb. Br J Clin Pharmacol. 2002 Dec;54(6):643-51. doi: 10.1046/j.1365-2125.2002.01687.x. Br J Clin Pharmacol. 2002. PMID: 12492613 Free PMC article. Clinical Trial.
Contributions of CYP3A4, P-glycoprotein, and serum protein binding to the intestinal first-pass extraction of saquinavir.
Mouly SJ, Paine MF, Watkins PB. Mouly SJ, et al. Among authors: watkins pb. J Pharmacol Exp Ther. 2004 Mar;308(3):941-8. doi: 10.1124/jpet.103.056390. Epub 2004 Jan 8. J Pharmacol Exp Ther. 2004. PMID: 14718607
6'7'-Dihydroxybergamottin contributes to the grapefruit juice effect.
Kakar SM, Paine MF, Stewart PW, Watkins PB. Kakar SM, et al. Among authors: watkins pb. Clin Pharmacol Ther. 2004 Jun;75(6):569-79. doi: 10.1016/j.clpt.2004.02.007. Clin Pharmacol Ther. 2004. PMID: 15179411 Clinical Trial.
Two major grapefruit juice components differ in time to onset of intestinal CYP3A4 inhibition.
Paine MF, Criss AB, Watkins PB. Paine MF, et al. Among authors: watkins pb. J Pharmacol Exp Ther. 2005 Mar;312(3):1151-60. doi: 10.1124/jpet.104.076836. Epub 2004 Oct 14. J Pharmacol Exp Ther. 2005. PMID: 15485894
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