Watkins PB - Search Results

1

Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia.

Zhou C, Assem M, Tay JC, Watkins PB, Blumberg B, Schuetz EG, Thummel KE. Zhou C, et al. Among authors: watkins pb. J Clin Invest. 2006 Jun;116(6):1703-12. doi: 10.1172/JCI27793. Epub 2006 May 11. J Clin Invest. 2006. PMID: 16691293 Free PMC article.

2

Induction of digitoxigenin monodigitoxoside UDP-glucuronosyltransferase activity by glucocorticoids and other inducers of cytochrome P-450p in primary monolayer cultures of adult rat hepatocytes and in human liver.

Schuetz EG, Hazelton GA, Hall J, Watkins PB, Klaassen CD, Guzelian PS. Schuetz EG, et al. Among authors: watkins pb. J Biol Chem. 1986 Jun 25;261(18):8270-5. J Biol Chem. 1986. PMID: 3087972 Free article.

3

Macrolide antibiotics inhibit the degradation of the glucocorticoid-responsive cytochrome P-450p in rat hepatocytes in vivo and in primary monolayer culture.

Watkins PB, Wrighton SA, Schuetz EG, Maurel P, Guzelian PS. Watkins PB, et al. J Biol Chem. 1986 May 15;261(14):6264-71. J Biol Chem. 1986. PMID: 3486184 Free article.

4

Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man.

Watkins PB, Wrighton SA, Schuetz EG, Molowa DT, Guzelian PS. Watkins PB, et al. J Clin Invest. 1987 Oct;80(4):1029-36. doi: 10.1172/JCI113156. J Clin Invest. 1987. PMID: 3654968 Free PMC article.

5

The erythromycin breath test predicts the clearance of midazolam.

Lown KS, Thummel KE, Benedict PE, Shen DD, Turgeon DK, Berent S, Watkins PB. Lown KS, et al. Among authors: watkins pb. Clin Pharmacol Ther. 1995 Jan;57(1):16-24. doi: 10.1016/0009-9236(95)90261-9. Clin Pharmacol Ther. 1995. PMID: 7828377 Free article.

6

Interpatient heterogeneity in expression of CYP3A4 and CYP3A5 in small bowel. Lack of prediction by the erythromycin breath test.

Lown KS, Kolars JC, Thummel KE, Barnett JL, Kunze KL, Wrighton SA, Watkins PB. Lown KS, et al. Among authors: watkins pb. Drug Metab Dispos. 1994 Nov-Dec;22(6):947-55. Drug Metab Dispos. 1994. PMID: 7895614

7

Selective expression of CYP3A5 and not CYP3A4 in human blood.

Janardan SK, Lown KS, Schmiedlin-Ren P, Thummel KE, Watkins PB. Janardan SK, et al. Among authors: watkins pb. Pharmacogenetics. 1996 Oct;6(5):379-85. doi: 10.1097/00008571-199610000-00001. Pharmacogenetics. 1996. PMID: 8946469

8

Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1alpha,25-dihydroxyvitamin D3.

Schmiedlin-Ren P, Thummel KE, Fisher JM, Paine MF, Lown KS, Watkins PB. Schmiedlin-Ren P, et al. Among authors: watkins pb. Mol Pharmacol. 1997 May;51(5):741-54. doi: 10.1124/mol.51.5.741. Mol Pharmacol. 1997. PMID: 9145912

9

Molecular and physical mechanisms of first-pass extraction.

Hall SD, Thummel KE, Watkins PB, Lown KS, Benet LZ, Paine MF, Mayo RR, Turgeon DK, Bailey DG, Fontana RJ, Wrighton SA. Hall SD, et al. Among authors: watkins pb. Drug Metab Dispos. 1999 Feb;27(2):161-6. Drug Metab Dispos. 1999. PMID: 9929497 Review.

10

First-pass midazolam metabolism catalyzed by 1alpha,25-dihydroxy vitamin D3-modified Caco-2 cell monolayers.

Fisher JM, Wrighton SA, Watkins PB, Schmiedlin-Ren P, Calamia JC, Shen DD, Kunze KL, Thummel KE. Fisher JM, et al. Among authors: watkins pb. J Pharmacol Exp Ther. 1999 May;289(2):1134-42. J Pharmacol Exp Ther. 1999. PMID: 10215697

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