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28 results
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Genetic background modifies phenotypic severity and longevity in a mouse model of Niemann-Pick disease type C1.
Rodriguez-Gil JL, Watkins-Chow DE, Baxter LL, Elliot G, Harper UL, Wincovitch SM, Wedel JC, Incao AA, Huebecker M, Boehm FJ, Garver WS, Porter FD, Broman KW, Platt FM, Pavan WJ. Rodriguez-Gil JL, et al. Among authors: Watkins-Chow DE. Dis Model Mech. 2020 Jan 29;13(3):dmm042614. doi: 10.1242/dmm.042614. Online ahead of print. Dis Model Mech. 2020. PMID: 31996359 Free PMC article.
NPC1 Deficiency in Mice is Associated with Fetal Growth Restriction, Neonatal Lethality and Abnormal Lung Pathology.
Rodriguez-Gil JL, Watkins-Chow DE, Baxter LL, Yokoyama T, Zerfas PM, Starost MF, Gahl WA, Malicdan MCV, Porter FD, Platt FM, Pavan WJ. Rodriguez-Gil JL, et al. Among authors: Watkins-Chow DE. J Clin Med. 2019 Dec 19;9(1):12. doi: 10.3390/jcm9010012. J Clin Med. 2019. PMID: 31861571 Free PMC article.
A curated gene list for expanding the horizons of pigmentation biology.
Baxter LL, Watkins-Chow DE, Pavan WJ, Loftus SK. Baxter LL, et al. Among authors: Watkins-Chow DE. Pigment Cell Melanoma Res. 2019 May;32(3):348-358. doi: 10.1111/pcmr.12743. Epub 2018 Nov 6. Pigment Cell Melanoma Res. 2019. PMID: 30339321 Review.
In Niemann-Pick C1 mouse models, glial-only expression of the normal gene extends survival much further than do changes in genetic background or treatment with hydroxypropyl-beta-cyclodextrin.
Marshall CA, Watkins-Chow DE, Palladino G, Deutsch G, Chandran K, Pavan WJ, Erickson RP. Marshall CA, et al. Among authors: Watkins-Chow DE. Gene. 2018 Feb 15;643:117-123. doi: 10.1016/j.gene.2017.12.006. Epub 2017 Dec 6. Gene. 2018. PMID: 29223359
Loci associated with skin pigmentation identified in African populations.
Crawford NG, Kelly DE, Hansen MEB, Beltrame MH, Fan S, Bowman SL, Jewett E, Ranciaro A, Thompson S, Lo Y, Pfeifer SP, Jensen JD, Campbell MC, Beggs W, Hormozdiari F, Mpoloka SW, Mokone GG, Nyambo T, Meskel DW, Belay G, Haut J; NISC Comparative Sequencing Program, Rothschild H, Zon L, Zhou Y, Kovacs MA, Xu M, Zhang T, Bishop K, Sinclair J, Rivas C, Elliot E, Choi J, Li SA, Hicks B, Burgess S, Abnet C, Watkins-Chow DE, Oceana E, Song YS, Eskin E, Brown KM, Marks MS, Loftus SK, Pavan WJ, Yeager M, Chanock S, Tishkoff SA. Crawford NG, et al. Among authors: Watkins-Chow DE. Science. 2017 Nov 17;358(6365):eaan8433. doi: 10.1126/science.aan8433. Epub 2017 Oct 12. Science. 2017. PMID: 29025994 Free PMC article.
BRG1 interacts with SOX10 to establish the melanocyte lineage and to promote differentiation.
Marathe HG, Watkins-Chow DE, Weider M, Hoffmann A, Mehta G, Trivedi A, Aras S, Basuroy T, Mehrotra A, Bennett DC, Wegner M, Pavan WJ, de la Serna IL. Marathe HG, et al. Among authors: Watkins-Chow DE, de la Serna IL. Nucleic Acids Res. 2017 Jun 20;45(11):6442-6458. doi: 10.1093/nar/gkx259. Nucleic Acids Res. 2017. PMID: 28431046 Free PMC article.
Correction: Mutation of the Diamond-Blackfan Anemia Gene Rps7 in Mouse Results in Morphological and Neuroanatomical Phenotypes.
Watkins-Chow DE, Cooke J, Pidsley R, Edwards A, Slotkin R, Leeds KE, Mullen R, Baxter LL, Campbell TG, Salzer MC, Biondini L, Gibney G, Tuy FP, Chelly J, Morris HD, Riegler J, Lythgoe MF, Arkell RM, Loreni F, Flint J, Pavan WJ, Keays DA. Watkins-Chow DE, et al. PLoS Genet. 2015 Nov 19;11(11):e1005682. doi: 10.1371/journal.pgen.1005682. eCollection 2015 Nov. PLoS Genet. 2015. PMID: 26584186 Free PMC article. No abstract available.
Genomic analysis reveals distinct mechanisms and functional classes of SOX10-regulated genes in melanocytes.
Fufa TD, Harris ML, Watkins-Chow DE, Levy D, Gorkin DU, Gildea DE, Song L, Safi A, Crawford GE, Sviderskaya EV, Bennett DC, Mccallion AS, Loftus SK, Pavan WJ. Fufa TD, et al. Among authors: Watkins-Chow DE. Hum Mol Genet. 2015 Oct 1;24(19):5433-50. doi: 10.1093/hmg/ddv267. Epub 2015 Jul 23. Hum Mol Genet. 2015. PMID: 26206884 Free PMC article.
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