Watkinson RE - Search Results

1

TRIM21 Promotes cGAS and RIG-I Sensing of Viral Genomes during Infection by Antibody-Opsonized Virus.

Watkinson RE, McEwan WA, Tam JC, Vaysburd M, James LC. Watkinson RE, et al. PLoS Pathog. 2015 Oct 27;11(10):e1005253. doi: 10.1371/journal.ppat.1005253. eCollection 2015 Oct. PLoS Pathog. 2015. PMID: 26506431 Free PMC article.

2

Simultaneous neutralization and innate immune detection of a replicating virus by TRIM21.

Watkinson RE, Tam JC, Vaysburd MJ, James LC. Watkinson RE, et al. J Virol. 2013 Jul;87(13):7309-13. doi: 10.1128/JVI.00647-13. Epub 2013 Apr 17. J Virol. 2013. PMID: 23596308 Free PMC article.

3

Intracellular antibody-bound pathogens stimulate immune signaling via the Fc receptor TRIM21.

McEwan WA, Tam JC, Watkinson RE, Bidgood SR, Mallery DL, James LC. McEwan WA, et al. Among authors: watkinson re. Nat Immunol. 2013 Apr;14(4):327-36. doi: 10.1038/ni.2548. Epub 2013 Mar 3. Nat Immunol. 2013. PMID: 23455675 Free PMC article.

4

Intracellular antibody receptor TRIM21 prevents fatal viral infection.

Vaysburd M, Watkinson RE, Cooper H, Reed M, O'Connell K, Smith J, Cruickshanks J, James LC. Vaysburd M, et al. Among authors: watkinson re. Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12397-401. doi: 10.1073/pnas.1301918110. Epub 2013 Jul 9. Proc Natl Acad Sci U S A. 2013. PMID: 23840060 Free PMC article.

5

Intracellular antibody immunity.

Watkinson RE, McEwan WA, James LC. Watkinson RE, et al. J Clin Immunol. 2014 Jul;34 Suppl 1:S30-4. doi: 10.1007/s10875-014-0017-4. Epub 2014 Apr 11. J Clin Immunol. 2014. PMID: 24722852 Review.

6

TRIM21: a cytosolic Fc receptor with broad antibody isotype specificity.

Foss S, Watkinson R, Sandlie I, James LC, Andersen JT. Foss S, et al. Immunol Rev. 2015 Nov;268(1):328-39. doi: 10.1111/imr.12363. Immunol Rev. 2015. PMID: 26497531 Free PMC article. Review.

7

Sequential ubiquitination and deubiquitination enzymes synchronize the dual sensor and effector functions of TRIM21.

Fletcher AJ, Mallery DL, Watkinson RE, Dickson CF, James LC. Fletcher AJ, et al. Among authors: watkinson re. Proc Natl Acad Sci U S A. 2015 Aug 11;112(32):10014-9. doi: 10.1073/pnas.1507534112. Epub 2015 Jul 6. Proc Natl Acad Sci U S A. 2015. PMID: 26150489 Free PMC article.

8

TRIM21 Immune Signaling Is More Sensitive to Antibody Affinity Than Its Neutralization Activity.

Foss S, Watkinson RE, Grevys A, McAdam MB, Bern M, Høydahl LS, Dalhus B, Michaelsen TE, Sandlie I, James LC, Andersen JT. Foss S, et al. Among authors: watkinson re. J Immunol. 2016 Apr 15;196(8):3452-3459. doi: 10.4049/jimmunol.1502601. Epub 2016 Mar 9. J Immunol. 2016. PMID: 26962230 Free PMC article.

9

Antibody-antigen kinetics constrain intracellular humoral immunity.

Bottermann M, Lode HE, Watkinson RE, Foss S, Sandlie I, Andersen JT, James LC. Bottermann M, et al. Among authors: watkinson re. Sci Rep. 2016 Nov 24;6:37457. doi: 10.1038/srep37457. Sci Rep. 2016. PMID: 27881870 Free PMC article.

10

Potent TRIM21 and complement-dependent intracellular antiviral immunity requires the IgG3 hinge.

Foss S, Jonsson A, Bottermann M, Watkinson R, Lode HE, McAdam MB, Michaelsen TE, Sandlie I, James LC, Andersen JT. Foss S, et al. Sci Immunol. 2022 Apr 29;7(70):eabj1640. doi: 10.1126/sciimmunol.abj1640. Epub 2022 Apr 29. Sci Immunol. 2022. PMID: 35486676 Free PMC article.

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