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Systematic discovery of natural CRISPR-Cas12a inhibitors.
Watters KE, Fellmann C, Bai HB, Ren SM, Doudna JA. Watters KE, et al. Science. 2018 Oct 12;362(6411):236-239. doi: 10.1126/science.aau5138. Epub 2018 Sep 6. Science. 2018. PMID: 30190307 Free PMC article.
Broad-spectrum enzymatic inhibition of CRISPR-Cas12a.
Knott GJ, Thornton BW, Lobba MJ, Liu JJ, Al-Shayeb B, Watters KE, Doudna JA. Knott GJ, et al. Among authors: watters ke. Nat Struct Mol Biol. 2019 Apr;26(4):315-321. doi: 10.1038/s41594-019-0208-z. Epub 2019 Apr 1. Nat Struct Mol Biol. 2019. PMID: 30936531 Free PMC article.
Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs.
Kundert K, Lucas JE, Watters KE, Fellmann C, Ng AH, Heineike BM, Fitzsimmons CM, Oakes BL, Qu J, Prasad N, Rosenberg OS, Savage DF, El-Samad H, Doudna JA, Kortemme T. Kundert K, et al. Among authors: watters ke. Nat Commun. 2019 May 9;10(1):2127. doi: 10.1038/s41467-019-09985-2. Nat Commun. 2019. PMID: 31073154 Free PMC article.
Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes.
Watters KE, Shivram H, Fellmann C, Lew RJ, McMahon B, Doudna JA. Watters KE, et al. Proc Natl Acad Sci U S A. 2020 Mar 24;117(12):6531-6539. doi: 10.1073/pnas.1917668117. Epub 2020 Mar 10. Proc Natl Acad Sci U S A. 2020. PMID: 32156733 Free PMC article.
Machine learning predicts new anti-CRISPR proteins.
Eitzinger S, Asif A, Watters KE, Iavarone AT, Knott GJ, Doudna JA, Minhas FUAA. Eitzinger S, et al. Among authors: watters ke. Nucleic Acids Res. 2020 May 21;48(9):4698-4708. doi: 10.1093/nar/gkaa219. Nucleic Acids Res. 2020. PMID: 32286628 Free PMC article.
The Fermi Gamma-Ray Space Telescope discovers the pulsar in the young galactic supernova remnant CTA 1.
Abdo AA, Ackermann M, Atwood WB, Baldini L, Ballet J, Barbiellini G, Baring MG, Bastieri D, Baughman BM, Bechtol K, Bellazzini R, Berenji B, Blandford RD, Bloom ED, Bogaert G, Bonamente E, Borgland AW, Bregeon J, Brez A, Brigida M, Bruel P, Burnett TH, Caliandro GA, Cameron RA, Caraveo PA, Carlson P, Casandjian JM, Cecchi C, Charles E, Chekhtman A, Cheung CC, Chiang J, Ciprini S, Claus R, Cohen-Tanugi J, Cominsky LR, Conrad J, Cutini S, Davis DS, Dermer CD, de Angelis A, de Palma F, Digel SW, Dormody M, do Couto E Silva E, Drell PS, Dubois R, Dumora D, Edmonds Y, Farnier C, Focke WB, Fukazawa Y, Funk S, Fusco P, Gargano F, Gasparrini D, Gehrels N, Germani S, Giebels B, Giglietto N, Giordano F, Glanzman T, Godfrey G, Grenier IA, Grondin MH, Grove JE, Guillemot L, Guiriec S, Harding AK, Hartman RC, Hays E, Hughes RE, Jóhannesson G, Johnson AS, Johnson RP, Johnson TJ, Johnson WN, Kamae T, Kanai Y, Kanbach G, Katagiri H, Kawai N, Kerr M, Kishishita T, Kiziltan B, Knödlseder J, Kocian ML, Komin N, Kuehn F, Kuss M, Latronico L, Lemoine-Goumard M, Longo F, Lonjou V, Loparco F, Lott B, Lovellette MN, Lubrano P, Makeev A, Marelli M, Mazziotta MN, McEnery JE, McGlynn S, Meurer C, Michelson … See abstract for full author list ➔ Abdo AA, et al. Science. 2008 Nov 21;322(5905):1218-21. doi: 10.1126/science.1165572. Epub 2008 Oct 16. Science. 2008. PMID: 18927355 Free article.
26 results