Watts RJ - Search Results

1

Developing therapeutic antibodies for neurodegenerative disease.

Yu YJ, Watts RJ. Yu YJ, et al. Among authors: watts rj. Neurotherapeutics. 2013 Jul;10(3):459-72. doi: 10.1007/s13311-013-0187-4. Neurotherapeutics. 2013. PMID: 23549647 Free PMC article. Review.

2

Function blocking antibodies to neuropilin-1 generated from a designed human synthetic antibody phage library.

Liang WC, Dennis MS, Stawicki S, Chanthery Y, Pan Q, Chen Y, Eigenbrot C, Yin J, Koch AW, Wu X, Ferrara N, Bagri A, Tessier-Lavigne M, Watts RJ, Wu Y. Liang WC, et al. Among authors: watts rj. J Mol Biol. 2007 Feb 23;366(3):815-29. doi: 10.1016/j.jmb.2006.11.021. Epub 2006 Nov 10. J Mol Biol. 2007. PMID: 17196977

3

Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth.

Pan Q, Chanthery Y, Liang WC, Stawicki S, Mak J, Rathore N, Tong RK, Kowalski J, Yee SF, Pacheco G, Ross S, Cheng Z, Le Couter J, Plowman G, Peale F, Koch AW, Wu Y, Bagri A, Tessier-Lavigne M, Watts RJ. Pan Q, et al. Among authors: watts rj. Cancer Cell. 2007 Jan;11(1):53-67. doi: 10.1016/j.ccr.2006.10.018. Cancer Cell. 2007. PMID: 17222790

4

Connecting vascular and nervous system development: angiogenesis and the blood-brain barrier.

Tam SJ, Watts RJ. Tam SJ, et al. Among authors: watts rj. Annu Rev Neurosci. 2010;33:379-408. doi: 10.1146/annurev-neuro-060909-152829. Annu Rev Neurosci. 2010. PMID: 20367445 Review.

5

Therapeutic antibody targeting of individual Notch receptors.

Wu Y, Cain-Hom C, Choy L, Hagenbeek TJ, de Leon GP, Chen Y, Finkle D, Venook R, Wu X, Ridgway J, Schahin-Reed D, Dow GJ, Shelton A, Stawicki S, Watts RJ, Zhang J, Choy R, Howard P, Kadyk L, Yan M, Zha J, Callahan CA, Hymowitz SG, Siebel CW. Wu Y, et al. Among authors: watts rj. Nature. 2010 Apr 15;464(7291):1052-7. doi: 10.1038/nature08878. Nature. 2010. PMID: 20393564

6

A therapeutic antibody targeting BACE1 inhibits amyloid-β production in vivo.

Atwal JK, Chen Y, Chiu C, Mortensen DL, Meilandt WJ, Liu Y, Heise CE, Hoyte K, Luk W, Lu Y, Peng K, Wu P, Rouge L, Zhang Y, Lazarus RA, Scearce-Levie K, Wang W, Wu Y, Tessier-Lavigne M, Watts RJ. Atwal JK, et al. Among authors: watts rj. Sci Transl Med. 2011 May 25;3(84):84ra43. doi: 10.1126/scitranslmed.3002254. Sci Transl Med. 2011. PMID: 21613622

7

Boosting brain uptake of a therapeutic antibody by reducing its affinity for a transcytosis target.

Yu YJ, Zhang Y, Kenrick M, Hoyte K, Luk W, Lu Y, Atwal J, Elliott JM, Prabhu S, Watts RJ, Dennis MS. Yu YJ, et al. Among authors: watts rj. Sci Transl Med. 2011 May 25;3(84):84ra44. doi: 10.1126/scitranslmed.3002230. Sci Transl Med. 2011. PMID: 21613623

8

Transferrin antibodies into the brain.

Dennis MS, Watts RJ. Dennis MS, et al. Among authors: watts rj. Neuropsychopharmacology. 2012 Jan;37(1):302-3. doi: 10.1038/npp.2011.196. Neuropsychopharmacology. 2012. PMID: 22157868 Free PMC article. No abstract available.

9

Death receptors DR6 and TROY regulate brain vascular development.

Tam SJ, Richmond DL, Kaminker JS, Modrusan Z, Martin-McNulty B, Cao TC, Weimer RM, Carano RA, van Bruggen N, Watts RJ. Tam SJ, et al. Among authors: watts rj. Dev Cell. 2012 Feb 14;22(2):403-17. doi: 10.1016/j.devcel.2011.11.018. Dev Cell. 2012. PMID: 22340501

10

Pharmacokinetic and pharmacodynamic analysis of circulating biomarkers of anti-NRP1, a novel antiangiogenesis agent, in two phase I trials in patients with advanced solid tumors.

Xin Y, Li J, Wu J, Kinard R, Weekes CD, Patnaik A, Lorusso P, Brachmann R, Tong RK, Yan Y, Watts R, Bai S, Hegde PS. Xin Y, et al. Clin Cancer Res. 2012 Nov 1;18(21):6040-8. doi: 10.1158/1078-0432.CCR-12-1652. Epub 2012 Sep 7. Clin Cancer Res. 2012. PMID: 22962439 Clinical Trial.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

Search Page

Search Results