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The interleukin-8 pathway in cancer.
Waugh DJ, Wilson C. Waugh DJ, et al. Clin Cancer Res. 2008 Nov 1;14(21):6735-41. doi: 10.1158/1078-0432.CCR-07-4843. Clin Cancer Res. 2008. PMID: 18980965 Review.
CD44 increases the efficiency of distant metastasis of breast cancer.
McFarlane S, Coulter JA, Tibbits P, O'Grady A, McFarlane C, Montgomery N, Hill A, McCarthy HO, Young LS, Kay EW, Isacke CM, Waugh DJ. McFarlane S, et al. Among authors: waugh dj. Oncotarget. 2015 May 10;6(13):11465-76. doi: 10.18632/oncotarget.3410. Oncotarget. 2015. PMID: 25888636 Free PMC article.
Tumor-derived CXCL8 signaling augments stroma-derived CCL2-promoted proliferation and CXCL12-mediated invasion of PTEN-deficient prostate cancer cells.
Maxwell PJ, Neisen J, Messenger J, Waugh DJ. Maxwell PJ, et al. Among authors: waugh dj. Oncotarget. 2014 Jul 15;5(13):4895-908. doi: 10.18632/oncotarget.2052. Oncotarget. 2014. PMID: 24970800 Free PMC article.
TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities.
D'Costa ZC, Higgins C, Ong CW, Irwin GW, Boyle D, McArt DG, McCloskey K, Buckley NE, Crawford NT, Thiagarajan L, Murray JT, Kennedy RD, Mulligan KA, Harkin DP, Waugh DJ, Scott CJ, Salto-Tellez M, Williams R, Mullan PB. D'Costa ZC, et al. Among authors: waugh dj. Oncotarget. 2014 Mar 30;5(6):1609-20. doi: 10.18632/oncotarget.1707. Oncotarget. 2014. PMID: 24742492 Free PMC article.
Potentiation of inflammatory CXCL8 signalling sustains cell survival in PTEN-deficient prostate carcinoma.
Maxwell PJ, Coulter J, Walker SM, McKechnie M, Neisen J, McCabe N, Kennedy RD, Salto-Tellez M, Albanese C, Waugh DJ. Maxwell PJ, et al. Among authors: waugh dj. Eur Urol. 2013 Aug;64(2):177-88. doi: 10.1016/j.eururo.2012.08.032. Epub 2012 Aug 28. Eur Urol. 2013. PMID: 22939387 Free PMC article.
Elevation of c-FLIP in castrate-resistant prostate cancer antagonizes therapeutic response to androgen receptor-targeted therapy.
McCourt C, Maxwell P, Mazzucchelli R, Montironi R, Scarpelli M, Salto-Tellez M, O'Sullivan JM, Longley DB, Waugh DJ. McCourt C, et al. Among authors: waugh dj. Clin Cancer Res. 2012 Jul 15;18(14):3822-33. doi: 10.1158/1078-0432.CCR-11-3277. Epub 2012 May 23. Clin Cancer Res. 2012. PMID: 22623731 Free PMC article.
CD44 enhances invasion of basal-like breast cancer cells by upregulating serine protease and collagen-degrading enzymatic expression and activity.
Montgomery N, Hill A, McFarlane S, Neisen J, O'Grady A, Conlon S, Jirstrom K, Kay EW, Waugh DJ. Montgomery N, et al. Among authors: waugh dj. Breast Cancer Res. 2012 May 23;14(3):R84. doi: 10.1186/bcr3199. Breast Cancer Res. 2012. PMID: 22621373 Free PMC article.
Interleukin-8 signaling attenuates TRAIL- and chemotherapy-induced apoptosis through transcriptional regulation of c-FLIP in prostate cancer cells.
Wilson C, Wilson T, Johnston PG, Longley DB, Waugh DJ. Wilson C, et al. Among authors: waugh dj. Mol Cancer Ther. 2008 Sep;7(9):2649-61. doi: 10.1158/1535-7163.MCT-08-0148. Mol Cancer Ther. 2008. PMID: 18790747
Chemotherapy-induced CXC-chemokine/CXC-chemokine receptor signaling in metastatic prostate cancer cells confers resistance to oxaliplatin through potentiation of nuclear factor-kappaB transcription and evasion of apoptosis.
Wilson C, Purcell C, Seaton A, Oladipo O, Maxwell PJ, O'Sullivan JM, Wilson RH, Johnston PG, Waugh DJ. Wilson C, et al. Among authors: waugh dj. J Pharmacol Exp Ther. 2008 Dec;327(3):746-59. doi: 10.1124/jpet.108.143826. Epub 2008 Sep 9. J Pharmacol Exp Ther. 2008. PMID: 18780829
Multi-faceted roles for CXC-chemokines in prostate cancer progression.
Waugh DJ, Wilson C, Seaton A, Maxwell PJ. Waugh DJ, et al. Front Biosci. 2008 May 1;13:4595-604. doi: 10.2741/3025. Front Biosci. 2008. PMID: 18508531 Review.
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