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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 1
2005 1
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2008 1
2009 2
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2014 3
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2016 4
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2020 3
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42 results

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Page 1
RTx-303, an Orally Bioavailable Polθ Polymerase Inhibitor That Potentiates PARP Inhibitors in BRCA Mutant Tumors.
Chandramouly G, Fried W, Gordon J, Ralph D, Keuk C, Kumari S, Ramanjulu M, Auerbacher W, Minakhin L, Tredinnick T, Tiberi B, Morton G, Betsch R, Cai KQ, Vekariya UM, Tyagi M, Skorski T, Karakashev S, Johnson N, Childers WE Jr, Chen XS, Pomerantz RT. Chandramouly G, et al. Among authors: childers we jr. J Med Chem. 2025 Nov 13;68(21):22196-22215. doi: 10.1021/acs.jmedchem.5c00551. Epub 2025 Oct 22. J Med Chem. 2025. PMID: 41124685 Free PMC article.
The Resurrection of Phenotypic Drug Discovery.
Childers WE, Elokely KM, Abou-Gharbia M. Childers WE, et al. ACS Med Chem Lett. 2020 Mar 6;11(10):1820-1828. doi: 10.1021/acsmedchemlett.0c00006. eCollection 2020 Oct 8. ACS Med Chem Lett. 2020. PMID: 33062159 Free PMC article.
"I'll Be Back": The Resurrection of Dezocine.
Childers WE, Abou-Gharbia MA. Childers WE, et al. ACS Med Chem Lett. 2021 May 19;12(6):961-968. doi: 10.1021/acsmedchemlett.1c00233. eCollection 2021 Jun 10. ACS Med Chem Lett. 2021. PMID: 34141081 Free PMC article.
Structure-Activity Relationship of a Pyrrole Based Series of PfPKG Inhibitors as Anti-Malarials.
Gilleran JA, Ashraf K, Delvillar M, Eck T, Fondekar R, Miller EB, Hutchinson A, Dong A, Seitova A, De Souza ML, Augeri D, Halabelian L, Siekierka J, Rotella DP, Gordon J, Childers WE, Grier MC, Staker BL, Roberge JY, Bhanot P. Gilleran JA, et al. Among authors: childers we. J Med Chem. 2024 Mar 14;67(5):3467-3503. doi: 10.1021/acs.jmedchem.3c01795. Epub 2024 Feb 19. J Med Chem. 2024. PMID: 38372781
Non-NAD-like PARP-1 inhibitors in prostate cancer treatment.
Karpova Y, Wu C, Divan A, McDonnell ME, Hewlett E, Makhov P, Gordon J, Ye M, Reitz AB, Childers WE, Skorski T, Kolenko V, Tulin AV. Karpova Y, et al. Among authors: childers we. Biochem Pharmacol. 2019 Sep;167:149-162. doi: 10.1016/j.bcp.2019.03.021. Epub 2019 Mar 15. Biochem Pharmacol. 2019. PMID: 30880062 Free PMC article.
4'-Ethynyl-2'-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress.
Calbert ML, Chandramouly G, Adams CM, Saez-Ayala M, Kent T, Tyagi M, Ayyadevara VSSA, Wang Y, Krais JJ, Gordon J, Atkins J, Toma MM, Betzi S, Boghossian AS, Rees MG, Ronan MM, Roth JA, Goldman AR, Gorman N, Mitra R, Childers WE, Graña X, Skorski T, Johnson N, Hurtz C, Morelli X, Eischen CM, Pomerantz RT. Calbert ML, et al. Among authors: childers we. Mol Cancer Ther. 2024 May 2;23(5):683-699. doi: 10.1158/1535-7163.MCT-23-0487. Mol Cancer Ther. 2024. PMID: 38064712 Free PMC article.
42 results