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Inducible gene expression: diverse regulatory mechanisms.
Weake VM, Workman JL. Weake VM, et al. Nat Rev Genet. 2010 Jun;11(6):426-37. doi: 10.1038/nrg2781. Epub 2010 Apr 27. Nat Rev Genet. 2010. PMID: 20421872 Review.
The Spliceosomal Protein SF3B5 is a Novel Component of Drosophila SAGA that Functions in Gene Expression Independent of Splicing.
Stegeman R, Spreacker PJ, Swanson SK, Stephenson R, Florens L, Washburn MP, Weake VM. Stegeman R, et al. J Mol Biol. 2016 Sep 11;428(18):3632-49. doi: 10.1016/j.jmb.2016.05.009. Epub 2016 May 13. J Mol Biol. 2016. PMID: 27185460 Free PMC article.
Post-transcription initiation function of the ubiquitous SAGA complex in tissue-specific gene activation.
Weake VM, Dyer JO, Seidel C, Box A, Swanson SK, Peak A, Florens L, Washburn MP, Abmayr SM, Workman JL. Weake VM, et al. Genes Dev. 2011 Jul 15;25(14):1499-509. doi: 10.1101/gad.2046211. Genes Dev. 2011. PMID: 21764853 Free PMC article.
Myeloid Leukemia Factor Acts in a Chaperone Complex to Regulate Transcription Factor Stability and Gene Expression.
Dyer JO, Dutta A, Gogol M, Weake VM, Dialynas G, Wu X, Seidel C, Zhang Y, Florens L, Washburn MP, Abmayr SM, Workman JL. Dyer JO, et al. J Mol Biol. 2017 Jun 30;429(13):2093-2107. doi: 10.1016/j.jmb.2016.10.026. Epub 2016 Oct 27. J Mol Biol. 2017. PMID: 27984043 Free PMC article.
Loss of Drosophila Ataxin-7, a SAGA subunit, reduces H2B ubiquitination and leads to neural and retinal degeneration.
Mohan RD, Dialynas G, Weake VM, Liu J, Martin-Brown S, Florens L, Washburn MP, Workman JL, Abmayr SM. Mohan RD, et al. Genes Dev. 2014 Feb 1;28(3):259-72. doi: 10.1101/gad.225151.113. Genes Dev. 2014. PMID: 24493646 Free PMC article.
SAGA function in tissue-specific gene expression.
Weake VM, Workman JL. Weake VM, et al. Trends Cell Biol. 2012 Apr;22(4):177-84. doi: 10.1016/j.tcb.2011.11.005. Epub 2011 Dec 21. Trends Cell Biol. 2012. PMID: 22196215 Free PMC article.
A novel histone fold domain-containing protein that replaces TAF6 in Drosophila SAGA is required for SAGA-dependent gene expression.
Weake VM, Swanson SK, Mushegian A, Florens L, Washburn MP, Abmayr SM, Workman JL. Weake VM, et al. Genes Dev. 2009 Dec 15;23(24):2818-23. doi: 10.1101/gad.1846409. Genes Dev. 2009. PMID: 20008933 Free PMC article.
Clearing the way for unpaused polymerases.
Weake VM, Workman JL. Weake VM, et al. Cell. 2008 Jul 11;134(1):16-8. doi: 10.1016/j.cell.2008.06.031. Cell. 2008. PMID: 18614004
Histone ubiquitination: triggering gene activity.
Weake VM, Workman JL. Weake VM, et al. Mol Cell. 2008 Mar 28;29(6):653-63. doi: 10.1016/j.molcel.2008.02.014. Mol Cell. 2008. PMID: 18374642 Review.
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