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Experimental demonstration of T:(G:G:G:G):T hexad and T:A:A:T tetrad alignments within a DNA quadruplex stem.
Webba da Silva M. Webba da Silva M. Biochemistry. 2005 Mar 15;44(10):3754-64. doi: 10.1021/bi0478190. Biochemistry. 2005. PMID: 15751952
A template-based approach was used to design unprecedented architectural motifs into a known DNA framework. The structure formed by the sequence d(GCGGTTGGAT) in 0.1 M Na(+) solution has been determined using molecular dynamics simulations constrained by distance and dihed …
A template-based approach was used to design unprecedented architectural motifs into a known DNA framework. The structure formed by the sequ …
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