Discovery of potent and selective inhibitors of human NLRP3 with a novel mechanism of action.
Wilhelmsen K, Deshpande A, Tronnes S, Mahanta M, Banicki M, Cochran M, Cowdin S, Fortney K, Hartman G, Hughes RE, Montgomery R, Portillo CP, Rubin P, Salazar T, Wang Y, Yan S, Morgan BA, Duisembekova A, Riou R, Marleaux M, Hochheiser IV, Buthmann H, Ferber D, Torp J, Wang W, Cranston M, McKee CM, Mawhinney TJ, McKay EC, Eroglu FK, Kümmerle-Deschner J, Weber ANR, Py BF, Geyer M, Coll RC.
Wilhelmsen K, et al. Among authors: weber anr.
J Exp Med. 2025 Nov 3;222(11):e20242403. doi: 10.1084/jem.20242403. Epub 2025 Sep 2.
J Exp Med. 2025.
PMID: 40892070
Free PMC article.