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The inositol polyphosphate 5-phosphatase OCRL1 restricts intracellular growth of Legionella, localizes to the replicative vacuole and binds to the bacterial effector LpnE.
Weber SS, Ragaz C, Hilbi H. Weber SS, et al. Cell Microbiol. 2009 Mar;11(3):442-60. doi: 10.1111/j.1462-5822.2008.01266.x. Epub 2008 Nov 13. Cell Microbiol. 2009. PMID: 19021631
How type 1 fimbriae help Escherichia coli to evade extracellular antibiotics.
Avalos Vizcarra I, Hosseini V, Kollmannsberger P, Meier S, Weber SS, Arnoldini M, Ackermann M, Vogel V. Avalos Vizcarra I, et al. Sci Rep. 2016 Jan 5;6:18109. doi: 10.1038/srep18109. Sci Rep. 2016. PMID: 26728082 Free PMC article.
Assessment of legionella-specific immunity in mice.
Weber SS, Joller N, Oxenius A. Weber SS, et al. Methods Mol Biol. 2013;954:505-20. doi: 10.1007/978-1-62703-161-5_31. Methods Mol Biol. 2013. PMID: 23150417
Immunofluorescence imaging of legionella infection in vitro.
Weber SS, Oxenius A. Weber SS, et al. Methods Mol Biol. 2013;954:265-77. doi: 10.1007/978-1-62703-161-5_16. Methods Mol Biol. 2013. PMID: 23150402
Antibodies protect against intracellular bacteria by Fc receptor-mediated lysosomal targeting.
Joller N, Weber SS, Müller AJ, Spörri R, Selchow P, Sander P, Hilbi H, Oxenius A. Joller N, et al. Proc Natl Acad Sci U S A. 2010 Nov 23;107(47):20441-6. doi: 10.1073/pnas.1013827107. Epub 2010 Nov 3. Proc Natl Acad Sci U S A. 2010. PMID: 21048081 Free PMC article.
Pathogen trafficking pathways and host phosphoinositide metabolism.
Weber SS, Ragaz C, Hilbi H. Weber SS, et al. Mol Microbiol. 2009 Mar;71(6):1341-52. doi: 10.1111/j.1365-2958.2009.06608.x. Epub 2009 Feb 4. Mol Microbiol. 2009. PMID: 19208094 Review.
Rab1 guanine nucleotide exchange factor SidM is a major phosphatidylinositol 4-phosphate-binding effector protein of Legionella pneumophila.
Brombacher E, Urwyler S, Ragaz C, Weber SS, Kami K, Overduin M, Hilbi H. Brombacher E, et al. J Biol Chem. 2009 Feb 20;284(8):4846-56. doi: 10.1074/jbc.M807505200. Epub 2008 Dec 17. J Biol Chem. 2009. PMID: 19095644 Free PMC article.
The Legionella pneumophila phosphatidylinositol-4 phosphate-binding type IV substrate SidC recruits endoplasmic reticulum vesicles to a replication-permissive vacuole.
Ragaz C, Pietsch H, Urwyler S, Tiaden A, Weber SS, Hilbi H. Ragaz C, et al. Cell Microbiol. 2008 Dec;10(12):2416-33. doi: 10.1111/j.1462-5822.2008.01219.x. Epub 2008 Aug 15. Cell Microbiol. 2008. PMID: 18673369
The Legionella pneumophila response regulator LqsR promotes host cell interactions as an element of the virulence regulatory network controlled by RpoS and LetA.
Tiaden A, Spirig T, Weber SS, Brüggemann H, Bosshard R, Buchrieser C, Hilbi H. Tiaden A, et al. Cell Microbiol. 2007 Dec;9(12):2903-20. doi: 10.1111/j.1462-5822.2007.01005.x. Epub 2007 Jul 5. Cell Microbiol. 2007. PMID: 17614967
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