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Colchicine for acute gout.
van Echteld I, Wechalekar MD, Schlesinger N, Buchbinder R, Aletaha D. van Echteld I, et al. Cochrane Database Syst Rev. 2014 Aug 15;(8):CD006190. doi: 10.1002/14651858.CD006190.pub2. Cochrane Database Syst Rev. 2014. PMID: 25123076 Review.
Intra-articular glucocorticoids for acute gout.
Wechalekar MD, Vinik O, Schlesinger N, Buchbinder R. Wechalekar MD, et al. Cochrane Database Syst Rev. 2013 Apr 30;(4):CD009920. doi: 10.1002/14651858.CD009920.pub2. Cochrane Database Syst Rev. 2013. PMID: 23633379 Review.
Multinational evidence-based recommendations for the diagnosis and management of gout: integrating systematic literature review and expert opinion of a broad panel of rheumatologists in the 3e initiative.
Sivera F, Andrés M, Carmona L, Kydd AS, Moi J, Seth R, Sriranganathan M, van Durme C, van Echteld I, Vinik O, Wechalekar MD, Aletaha D, Bombardier C, Buchbinder R, Edwards CJ, Landewé RB, Bijlsma JW, Branco JC, Burgos-Vargas R, Catrina AI, Elewaut D, Ferrari AJ, Kiely P, Leeb BF, Montecucco C, Müller-Ladner U, Ostergaard M, Zochling J, Falzon L, van der Heijde DM. Sivera F, et al. Ann Rheum Dis. 2014 Feb;73(2):328-35. doi: 10.1136/annrheumdis-2013-203325. Epub 2013 Jul 18. Ann Rheum Dis. 2014. PMID: 23868909 Free PMC article.
Interleukin-1 inhibitors for acute gout.
Sivera F, Wechalekar MD, Andrés M, Buchbinder R, Carmona L. Sivera F, et al. Cochrane Database Syst Rev. 2014 Sep 1;(9):CD009993. doi: 10.1002/14651858.CD009993.pub2. Cochrane Database Syst Rev. 2014. PMID: 25177840 Review.
Moderate-quality evidence indicated that canakinumab 150 mg was probably superior to triamcinolone acetonide 40 mg in terms of pain relief, resolution of joint swelling and in achieving a good treatment response at 72 hours following treatment, but was probably associated with an …
Moderate-quality evidence indicated that canakinumab 150 mg was probably superior to triamcinolone acetonide 40 mg in terms of pain relief, …
The efficacy and safety of treatments for acute gout: results from a series of systematic literature reviews including Cochrane reviews on intraarticular glucocorticoids, colchicine, nonsteroidal antiinflammatory drugs, and interleukin-1 inhibitors.
Wechalekar MD, Vinik O, Moi JH, Sivera F, van Echteld IA, van Durme C, Falzon L, Bombardier C, Carmona L, Aletaha D, Landewé RB, van der Heijde DM, Buchbinder R. Wechalekar MD, et al. J Rheumatol Suppl. 2014 Sep;92:15-25. doi: 10.3899/jrheum.140458. J Rheumatol Suppl. 2014. PMID: 25180124 Review.
Non-steroidal anti-inflammatory drugs for acute gout.
van Durme CM, Wechalekar MD, Buchbinder R, Schlesinger N, van der Heijde D, Landewé RB. van Durme CM, et al. Cochrane Database Syst Rev. 2014 Sep 16;(9):CD010120. doi: 10.1002/14651858.CD010120.pub2. Cochrane Database Syst Rev. 2014. PMID: 25225849 Review.
Joint swelling in the COXIB group was 1.64 points on a 0- to 3-point scale (0 is no swelling) and 0.13 points higher with NSAIDs (MD 0.13, 95% CI -0.08 to 0.34). ...Pain reduction was 9.5 on a 0- to 100-point scale with glucocorticoids, pain reduction with NSAIDs was 1.74 …
Joint swelling in the COXIB group was 1.64 points on a 0- to 3-point scale (0 is no swelling) and 0.13 points higher with NSAIDs (MD
Australian and New Zealand recommendations for the diagnosis and management of gout: integrating systematic literature review and expert opinion in the 3e Initiative.
Graf SW, Whittle SL, Wechalekar MD, Moi JH, Barrett C, Hill CL, Littlejohn G, Lynch N, Major G, Taylor AL, Buchbinder R, Zochling J. Graf SW, et al. Int J Rheum Dis. 2015 Mar;18(3):341-51. doi: 10.1111/1756-185X.12557. Epub 2015 Apr 17. Int J Rheum Dis. 2015. PMID: 25884565 Review.
Nonsteroidal anti-inflammatory drugs for treatment of acute gout.
van Durme CM, Wechalekar MD, Landewé RB. van Durme CM, et al. JAMA. 2015 Jun 9;313(22):2276-7. doi: 10.1001/jama.2015.1881. JAMA. 2015. PMID: 26057289
Active foot synovitis in patients with rheumatoid arthritis: applying clinical criteria for disease activity and remission may result in underestimation of foot joint involvement.
Wechalekar MD, Lester S, Proudman SM, Cleland LG, Whittle SL, Rischmueller M, Hill CL. Wechalekar MD, et al. Arthritis Rheum. 2012 May;64(5):1316-22. doi: 10.1002/art.33506. Arthritis Rheum. 2012. PMID: 22135142 Clinical Trial.
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