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Genetic background modifies phenotypic severity and longevity in a mouse model of Niemann-Pick disease type C1.
Rodriguez-Gil JL, Watkins-Chow DE, Baxter LL, Elliot G, Harper UL, Wincovitch SM, Wedel JC, Incao AA, Huebecker M, Boehm FJ, Garver WS, Porter FD, Broman KW, Platt FM, Pavan WJ. Rodriguez-Gil JL, et al. Among authors: Wedel JC. Dis Model Mech. 2020 Jan 29;13(3):dmm042614. doi: 10.1242/dmm.042614. Online ahead of print. Dis Model Mech. 2020. PMID: 31996359 Free PMC article.
MEK inhibition remodels the active chromatin landscape and induces SOX10 genomic recruitment in BRAF(V600E) mutant melanoma cells.
Fufa TD, Baxter LL, Wedel JC, Gildea DE; NISC Comparative Sequencing Program, Loftus SK, Pavan WJ. Fufa TD, et al. Among authors: Wedel JC. Epigenetics Chromatin. 2019 Aug 9;12(1):50. doi: 10.1186/s13072-019-0297-2. Epigenetics Chromatin. 2019. PMID: 31399133 Free PMC article.
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