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Pyridoxine-induced toxicity in rats: a stereological quantification of the sensory neuropathy.
Perry TA, Weerasuriya A, Mouton PR, Holloway HW, Greig NH. Perry TA, et al. Exp Neurol. 2004 Nov;190(1):133-44. doi: 10.1016/j.expneurol.2004.07.013. Exp Neurol. 2004. PMID: 15473987
Excess ingestion of pyridoxine (vitamin B6) causes a severe sensory neuropathy in humans. The mechanism of action has not been fully elucidated, and studies of pyridoxine neuropathy in experimental animals have yielded disparate results. ...This combined stereological and …
Excess ingestion of pyridoxine (vitamin B6) causes a severe sensory neuropathy in humans. The mechanism of action has not been fully …
Evidence of GLP-1-mediated neuroprotection in an animal model of pyridoxine-induced peripheral sensory neuropathy.
Perry T, Holloway HW, Weerasuriya A, Mouton PR, Duffy K, Mattison JA, Greig NH. Perry T, et al. Among authors: weerasuriya a. Exp Neurol. 2007 Feb;203(2):293-301. doi: 10.1016/j.expneurol.2006.09.028. Epub 2006 Nov 22. Exp Neurol. 2007. PMID: 17125767 Free PMC article.
Patterns of change in endoneurial capillary permeability and vascular space during nerve regeneration.
Weerasuriya A. Weerasuriya A. Brain Res. 1990 Feb 26;510(1):135-9. doi: 10.1016/0006-8993(90)90739-x. Brain Res. 1990. PMID: 2322838
There was a delayed increase of both PS and V which peaked at 2-3 weeks after the crush and then declined. This is strikingly similar to the pattern seen in transected nerves. ...This second peak of PS coincided with a rapid increase of the CAP amplitude and a
There was a delayed increase of both PS and V which peaked at 2-3 weeks after the crush and then declined. This is strikingly similar …
Permeability of endoneurial capillaries to K, Na and Cl and its relation to peripheral nerve excitability.
Weerasuriya A. Weerasuriya A. Brain Res. 1987 Sep 1;419(1-2):188-96. doi: 10.1016/0006-8993(87)90582-8. Brain Res. 1987. PMID: 3499951
The minimum extracellular K concentration (Ke) capable of producing a depolarization conduction block in frog sciatic nerve was between 12.5 and 15.0 mM. When the vasculature of this nerve was perfused with a hyperkalaemic (20.0 mM) Ringer solution, a conduct …
The minimum extracellular K concentration (Ke) capable of producing a depolarization conduction block in frog sciatic nerve was betwe …
Physiological changes in the sciatic nerve endoneurium of lead-intoxicated rats: a model of endoneurial homeostasis.
Weerasuriya A, Curran GL, Poduslo JF. Weerasuriya A, et al. Brain Res. 1990 May 28;517(1-2):1-6. doi: 10.1016/0006-8993(90)91000-7. Brain Res. 1990. PMID: 2165428
Thereafter, over the next 6 weeks, the blood Pb levels were relatively stable, while the endoneurial Pb levels decreased sharply to a quarter of their peak values. The wet/dry weight ratio of the endoneurium, an indicator of nerve oedema, increased by about 30% from the 4t …
Thereafter, over the next 6 weeks, the blood Pb levels were relatively stable, while the endoneurial Pb levels decreased sharply to a
Perineurial permeability increases during Wallerian degeneration.
Weerasuriya A, Rapoport SI, Taylor RE. Weerasuriya A, et al. Brain Res. 1980 Jun 23;192(2):581-5. doi: 10.1016/0006-8993(80)90911-7. Brain Res. 1980. PMID: 6966527 No abstract available.
Ionic permeabilities of the frog perineurium.
Weerasuriya A, Rapoport SI, Taylor RE. Weerasuriya A, et al. Brain Res. 1980 Jun 9;191(2):405-15. doi: 10.1016/0006-8993(80)91290-1. Brain Res. 1980. PMID: 6247016
A cylindrical segment of perineurium removed from the nerve and mounted in vitro on two cannulae was continuously perfused. Permeation rates of 22Na and 42K across the perineurium were the same in either direction and were unaffected by the drugs. ...
A cylindrical segment of perineurium removed from the nerve and mounted in vitro on two cannulae was continuously perfused. Permeatio
Modification of permeability of frog perineurium to [14C]-sucrose by stretch and hypertonicity.
Weerasuriya A, Rapoport SI, Taylor RE. Weerasuriya A, et al. Brain Res. 1979 Sep 21;173(3):503-12. doi: 10.1016/0006-8993(79)90244-0. Brain Res. 1979. PMID: 314830
A 10% stretch increased permeability reversibly, whereas a 20% stretch or immersion of the perineurium in a hypertonic bath increased permeability irreversibly. ...
A 10% stretch increased permeability reversibly, whereas a 20% stretch or immersion of the perineurium in a hypertonic
Basal forebrain facilitation of reflex swallowing in the cat.
Weerasuriya A, Bieger D, Hockman CH. Weerasuriya A, et al. Brain Res. 1979 Sep 28;174(1):119-33. doi: 10.1016/0006-8993(79)90808-4. Brain Res. 1979. PMID: 385108
A systematic stereotaxic mapping study using electrical stimulation revealed that the facilitatory sites were distributed along the course of the ansa peduncularis, specifically its rostral forebrain and hypothalamic components associated with the anterior amygdalar area,
A systematic stereotaxic mapping study using electrical stimulation revealed that the facilitatory sites were distributed along the c
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