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Identification of cancer driver genes based on nucleotide context.
Dietlein F, Weghorn D, Taylor-Weiner A, Richters A, Reardon B, Liu D, Lander ES, Van Allen EM, Sunyaev SR. Dietlein F, et al. Among authors: weghorn d. Nat Genet. 2020 Feb;52(2):208-218. doi: 10.1038/s41588-019-0572-y. Epub 2020 Feb 3. Nat Genet. 2020. PMID: 32015527 Free PMC article.
Reply to 'Selective effects of heterozygous protein-truncating variants'.
Cassa CA, Weghorn D, Balick DJ, Jordan DM, Nusinow D, Samocha KE, O'Donnell-Luria A, MacArthur DG, Daly MJ, Beier DR, Sunyaev SR. Cassa CA, et al. Among authors: weghorn d. Nat Genet. 2019 Jan;51(1):3-4. doi: 10.1038/s41588-018-0301-y. Nat Genet. 2019. PMID: 30478437 Free PMC article. No abstract available.
Germline de novo mutation rates on exons versus introns in humans.
Rodriguez-Galindo M, Casillas S, Weghorn D, Barbadilla A. Rodriguez-Galindo M, et al. Among authors: weghorn d. Nat Commun. 2020 Jul 3;11(1):3304. doi: 10.1038/s41467-020-17162-z. Nat Commun. 2020. PMID: 32620809 Free PMC article.
Fitness landscape for nucleosome positioning.
Weghorn D, Lässig M. Weghorn D, et al. Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):10988-93. doi: 10.1073/pnas.1210887110. Epub 2013 Jun 19. Proc Natl Acad Sci U S A. 2013. PMID: 23784778 Free PMC article.
Genes enriched in A/T-ending codons are co-regulated and conserved across mammals.
Benisty H, Hernandez-Alias X, Weber M, Anglada-Girotto M, Mantica F, Radusky L, Senger G, Calvet F, Weghorn D, Irimia M, Schaefer MH, Serrano L. Benisty H, et al. Among authors: weghorn d. Cell Syst. 2023 Apr 19;14(4):312-323.e3. doi: 10.1016/j.cels.2023.02.002. Epub 2023 Mar 7. Cell Syst. 2023. PMID: 36889307 Free article.