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Differential efficiency of induction of various lambdoid prophages responsible for production of Shiga toxins in response to different induction agents.
Loś JM, Loś M, Wegrzyn G, Wegrzyn A. Loś JM, et al. Microb Pathog. 2009 Dec;47(6):289-98. doi: 10.1016/j.micpath.2009.09.006. Epub 2009 Sep 15. Microb Pathog. 2009. PMID: 19761828
Shiga toxin-producing Escherichia coli (STEC) is a group of pathogenic strains responsible for bloody diarrhea and hemorrhagic colitis, with often severe complications. ...Therefore, a transition of the phage genome from the prophage state to an extrachromosomal gen …
Shiga toxin-producing Escherichia coli (STEC) is a group of pathogenic strains responsible for bloody diarrhea and hemorrhagic coliti …
Differential replication of plasmids during stringent and relaxed response of Escherichia coli.
Herman A, Wegrzyn A, Wegrzyn G. Herman A, et al. Plasmid. 1994 Jul;32(1):89-94. doi: 10.1006/plas.1994.1049. Plasmid. 1994. PMID: 7527562
Stringent control of DNA replication has been demonstrated for a few replicons like oriC, pBR322, and plasmids derived from coliphage lambda. In this study we investigated the replication of other plasmids harboring a well defined origin (orip15A, oripSC101, and ori …
Stringent control of DNA replication has been demonstrated for a few replicons like oriC, pBR322, and plasmids derived from coliphage …
Transcriptional activation of ori lambda regulates lambda plasmid replication in amino acid-starved Escherichia coli cells.
Wegrzyn A, Wegrzyn G. Wegrzyn A, et al. Biochem Biophys Res Commun. 1995 Sep 25;214(3):978-84. doi: 10.1006/bbrc.1995.2382. Biochem Biophys Res Commun. 1995. PMID: 7575572
On the basis of these findings and other recent reports, we demonstrate a model of the regulation of lambda plasmid replication driven by the inherited replication complex. ...
On the basis of these findings and other recent reports, we demonstrate a model of the regulation of lambda plasmid replication drive …
Involvement of the host initiator function dnaA in the replication of coliphage lambda.
Wegrzyn G, Wegrzyn A, Konieczny I, Bielawski K, Konopa G, Obuchowski M, Helinski DR, Taylor K. Wegrzyn G, et al. Genetics. 1995 Apr;139(4):1469-81. Genetics. 1995. PMID: 7789753 Free PMC article.
In dnaAts rac+ cells at 43 degrees, most of parental phage DNA molecules, after one round of theta replication, switched to a replication with features of the sigma mode and produced progeny at high yield. ...
In dnaAts rac+ cells at 43 degrees, most of parental phage DNA molecules, after one round of theta replication, switched to a replica …
Transcriptional activation of the origin of coliphage lambda DNA replication is regulated by the host DnaA initiator function.
Wegrzyn G, Szalewska-Pałasz A, Wegrzyn A, Obuchowski M, Taylor K. Wegrzyn G, et al. Gene. 1995 Feb 27;154(1):47-50. doi: 10.1016/0378-1119(94)00849-n. Gene. 1995. PMID: 7867947
Here, we demonstrate that lambda plasmid replication can be synchronized by a temperature shift-down that caused renaturation of the previously denatured DnaAts protein. ...Biol. 198 (1987) 203-210] and why the initiation of phage lambda DNA replication is blocked (in E. c …
Here, we demonstrate that lambda plasmid replication can be synchronized by a temperature shift-down that caused renaturation of the …
The mechanism of the stringent control of lambda plasmid DNA replication.
Szalewska-Pałasz A, Wegrzyn A, Herman A, Wegrzyn G. Szalewska-Pałasz A, et al. EMBO J. 1994 Dec 1;13(23):5779-85. EMBO J. 1994. PMID: 7988574 Free PMC article.
This replication is perpetuated by the replication complex containing the lambda O protein (which is protected from proteases by other elements of the complex) and inherited by one of two daughter copies after a replication round. ...The replacement of pR with plac (which …
This replication is perpetuated by the replication complex containing the lambda O protein (which is protected from proteases by other eleme …
Regulation of replication of plasmid pBR322 in amino acid-starved Escherichia coli strains.
Herman A, Wegrzyn A, Wegrzyn G. Herman A, et al. Mol Gen Genet. 1994 May 25;243(4):374-8. doi: 10.1007/BF00280467. Mol Gen Genet. 1994. PMID: 8202082
Moreover, pUC19, which is a pBR322-derived plasmid lacking the rom gene, behaves like pBR322rom-, whereas introduction of the rom gene into the pUC19 replicon drives it into the pBR322 mode of replication in amino acid-starved bacteria. A model for the regulation of …
Moreover, pUC19, which is a pBR322-derived plasmid lacking the rom gene, behaves like pBR322rom-, whereas introduction of the rom gen …
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