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220 results
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Ca2+/calmodulin-dependent protein kinase II phosphorylation regulates the cardiac ryanodine receptor.
Wehrens XH, Lehnart SE, Reiken SR, Marks AR. Wehrens XH, et al. Circ Res. 2004 Apr 2;94(6):e61-70. doi: 10.1161/01.RES.0000125626.33738.E2. Epub 2004 Mar 11. Circ Res. 2004. PMID: 15016728
Arrhythmogenic mechanism of an LQT-3 mutation of the human heart Na(+) channel alpha-subunit: A computational analysis.
Wehrens XH, Abriel H, Cabo C, Benhorin J, Kass RS. Wehrens XH, et al. Circulation. 2000 Aug 1;102(5):584-90. doi: 10.1161/01.cir.102.5.584. Circulation. 2000. PMID: 10920073
Molecular pharmacology of the sodium channel mutation D1790G linked to the long-QT syndrome.
Abriel H, Wehrens XH, Benhorin J, Kerem B, Kass RS. Abriel H, et al. Among authors: wehrens xh. Circulation. 2000 Aug 22;102(8):921-5. doi: 10.1161/01.cir.102.8.921. Circulation. 2000. PMID: 10952963
Novel arrhythmogenic mechanism revealed by a long-QT syndrome mutation in the cardiac Na(+) channel.
Abriel H, Cabo C, Wehrens XH, Rivolta I, Motoike HK, Memmi M, Napolitano C, Priori SG, Kass RS. Abriel H, et al. Among authors: wehrens xh. Circ Res. 2001 Apr 13;88(7):740-5. doi: 10.1161/hh0701.089668. Circ Res. 2001. PMID: 11304498
Non-equilibrium gating in cardiac Na+ channels: an original mechanism of arrhythmia.
Clancy CE, Tateyama M, Liu H, Wehrens XH, Kass RS. Clancy CE, et al. Among authors: wehrens xh. Circulation. 2003 May 6;107(17):2233-7. doi: 10.1161/01.CIR.0000069273.51375.BD. Epub 2003 Apr 14. Circulation. 2003. PMID: 12695286
Beta-blockers restore calcium release channel function and improve cardiac muscle performance in human heart failure.
Reiken S, Wehrens XH, Vest JA, Barbone A, Klotz S, Mancini D, Burkhoff D, Marks AR. Reiken S, et al. Among authors: wehrens xh. Circulation. 2003 May 20;107(19):2459-66. doi: 10.1161/01.CIR.0000068316.53218.49. Epub 2003 May 12. Circulation. 2003. PMID: 12743001 Clinical Trial.
FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death.
Wehrens XH, Lehnart SE, Huang F, Vest JA, Reiken SR, Mohler PJ, Sun J, Guatimosim S, Song LS, Rosemblit N, D'Armiento JM, Napolitano C, Memmi M, Priori SG, Lederer WJ, Marks AR. Wehrens XH, et al. Cell. 2003 Jun 27;113(7):829-40. doi: 10.1016/s0092-8674(03)00434-3. Cell. 2003. PMID: 12837242
Myocardial disease in failing hearts: defective excitation-contraction coupling.
Wehrens XH, Marks AR. Wehrens XH, et al. Cold Spring Harb Symp Quant Biol. 2002;67:533-41. doi: 10.1101/sqb.2002.67.533. Cold Spring Harb Symp Quant Biol. 2002. PMID: 12858580 Review. No abstract available.
Altered function and regulation of cardiac ryanodine receptors in cardiac disease.
Wehrens XH, Marks AR. Wehrens XH, et al. Trends Biochem Sci. 2003 Dec;28(12):671-8. doi: 10.1016/j.tibs.2003.10.003. Trends Biochem Sci. 2003. PMID: 14659699 Review.
Protection from cardiac arrhythmia through ryanodine receptor-stabilizing protein calstabin2.
Wehrens XH, Lehnart SE, Reiken SR, Deng SX, Vest JA, Cervantes D, Coromilas J, Landry DW, Marks AR. Wehrens XH, et al. Science. 2004 Apr 9;304(5668):292-6. doi: 10.1126/science.1094301. Science. 2004. PMID: 15073377
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