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Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models.
Schiffer M, Teng B, Gu C, Shchedrina VA, Kasaikina M, Pham VA, Hanke N, Rong S, Gueler F, Schroder P, Tossidou I, Park JK, Staggs L, Haller H, Erschow S, Hilfiker-Kleiner D, Wei C, Chen C, Tardi N, Hakroush S, Selig MK, Vasilyev A, Merscher S, Reiser J, Sever S. Schiffer M, et al. Among authors: wei c. Nat Med. 2015 Jun;21(6):601-9. doi: 10.1038/nm.3843. Epub 2015 May 11. Nat Med. 2015. PMID: 25962121 Free PMC article.
TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function.
Reiser J, Polu KR, Möller CC, Kenlan P, Altintas MM, Wei C, Faul C, Herbert S, Villegas I, Avila-Casado C, McGee M, Sugimoto H, Brown D, Kalluri R, Mundel P, Smith PL, Clapham DE, Pollak MR. Reiser J, et al. Among authors: wei c. Nat Genet. 2005 Jul;37(7):739-44. doi: 10.1038/ng1592. Epub 2005 May 27. Nat Genet. 2005. PMID: 15924139 Free PMC article.
Induction of TRPC6 channel in acquired forms of proteinuric kidney disease.
Möller CC, Wei C, Altintas MM, Li J, Greka A, Ohse T, Pippin JW, Rastaldi MP, Wawersik S, Schiavi S, Henger A, Kretzler M, Shankland SJ, Reiser J. Möller CC, et al. Among authors: wei c. J Am Soc Nephrol. 2007 Jan;18(1):29-36. doi: 10.1681/ASN.2006091010. Epub 2006 Dec 13. J Am Soc Nephrol. 2007. PMID: 17167110
Modification of kidney barrier function by the urokinase receptor.
Wei C, Möller CC, Altintas MM, Li J, Schwarz K, Zacchigna S, Xie L, Henger A, Schmid H, Rastaldi MP, Cowan P, Kretzler M, Parrilla R, Bendayan M, Gupta V, Nikolic B, Kalluri R, Carmeliet P, Mundel P, Reiser J. Wei C, et al. Nat Med. 2008 Jan;14(1):55-63. doi: 10.1038/nm1696. Epub 2007 Dec 16. Nat Med. 2008. PMID: 18084301
Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity.
Hartleben B, Schweizer H, Lübben P, Bartram MP, Möller CC, Herr R, Wei C, Neumann-Haefelin E, Schermer B, Zentgraf H, Kerjaschki D, Reiser J, Walz G, Benzing T, Huber TB. Hartleben B, et al. Among authors: wei c. J Biol Chem. 2008 Aug 22;283(34):23033-8. doi: 10.1074/jbc.M803143200. Epub 2008 Jun 18. J Biol Chem. 2008. PMID: 18562307 Free PMC article.
Rituximab targets podocytes in recurrent focal segmental glomerulosclerosis.
Fornoni A, Sageshima J, Wei C, Merscher-Gomez S, Aguillon-Prada R, Jauregui AN, Li J, Mattiazzi A, Ciancio G, Chen L, Zilleruelo G, Abitbol C, Chandar J, Seeherunvong W, Ricordi C, Ikehata M, Rastaldi MP, Reiser J, Burke GW 3rd. Fornoni A, et al. Among authors: wei c. Sci Transl Med. 2011 Jun 1;3(85):85ra46. doi: 10.1126/scitranslmed.3002231. Sci Transl Med. 2011. PMID: 21632984 Free PMC article.
Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis.
Wei C, El Hindi S, Li J, Fornoni A, Goes N, Sageshima J, Maiguel D, Karumanchi SA, Yap HK, Saleem M, Zhang Q, Nikolic B, Chaudhuri A, Daftarian P, Salido E, Torres A, Salifu M, Sarwal MM, Schaefer F, Morath C, Schwenger V, Zeier M, Gupta V, Roth D, Rastaldi MP, Burke G, Ruiz P, Reiser J. Wei C, et al. Nat Med. 2011 Jul 31;17(8):952-60. doi: 10.1038/nm.2411. Nat Med. 2011. PMID: 21804539 Free PMC article.
Small molecule-mediated activation of the integrin CD11b/CD18 reduces inflammatory disease.
Maiguel D, Faridi MH, Wei C, Kuwano Y, Balla KM, Hernandez D, Barth CJ, Lugo G, Donnelly M, Nayer A, Moita LF, Schürer S, Traver D, Ruiz P, Vazquez-Padron RI, Ley K, Reiser J, Gupta V. Maiguel D, et al. Among authors: wei c. Sci Signal. 2011 Sep 6;4(189):ra57. doi: 10.1126/scisignal.2001811. Sci Signal. 2011. PMID: 21900205 Free PMC article.
8,388 results