Wei J - Search Results

1

Understanding fibrosis in systemic sclerosis: shifting paradigms, emerging opportunities.

Bhattacharyya S, Wei J, Varga J. Bhattacharyya S, et al. Among authors: wei j. Nat Rev Rheumatol. 2011 Oct 25;8(1):42-54. doi: 10.1038/nrrheum.2011.149. Nat Rev Rheumatol. 2011. PMID: 22025123 Free PMC article. Review.

2

Constitutive Smad signaling and Smad-dependent collagen gene expression in mouse embryonic fibroblasts lacking peroxisome proliferator-activated receptor-gamma.

Ghosh AK, Wei J, Wu M, Varga J. Ghosh AK, et al. Among authors: wei j. Biochem Biophys Res Commun. 2008 Sep 19;374(2):231-6. doi: 10.1016/j.bbrc.2008.07.014. Epub 2008 Jul 15. Biochem Biophys Res Commun. 2008. PMID: 18627765 Free PMC article.

3

Peroxisome proliferator-activated receptor-gamma abrogates Smad-dependent collagen stimulation by targeting the p300 transcriptional coactivator.

Ghosh AK, Bhattacharyya S, Wei J, Kim S, Barak Y, Mori Y, Varga J. Ghosh AK, et al. Among authors: wei j. FASEB J. 2009 Sep;23(9):2968-77. doi: 10.1096/fj.08-128736. Epub 2009 Apr 24. FASEB J. 2009. PMID: 19395477 Free PMC article.

4

The transcriptional cofactor nab2 is induced by tgf-Beta and suppresses fibroblast activation: physiological roles and impaired expression in scleroderma.

Bhattacharyya S, Wei J, Melichian DS, Milbrandt J, Takehara K, Varga J. Bhattacharyya S, et al. Among authors: wei j. PLoS One. 2009 Oct 26;4(10):e7620. doi: 10.1371/journal.pone.0007620. PLoS One. 2009. PMID: 19888474 Free PMC article.

5

Peroxisome proliferator-activated receptor γ: innate protection from excessive fibrogenesis and potential therapeutic target in systemic sclerosis.

Wei J, Bhattacharyya S, Varga J. Wei J, et al. Curr Opin Rheumatol. 2010 Nov;22(6):671-6. doi: 10.1097/BOR.0b013e32833de1a7. Curr Opin Rheumatol. 2010. PMID: 20693905 Free PMC article. Review.

6

Fibrosis in systemic sclerosis: emerging concepts and implications for targeted therapy.

Wei J, Bhattacharyya S, Tourtellotte WG, Varga J. Wei J, et al. Autoimmun Rev. 2011 Mar;10(5):267-75. doi: 10.1016/j.autrev.2010.09.015. Epub 2010 Sep 21. Autoimmun Rev. 2011. PMID: 20863909 Free PMC article.

7

PPARγ downregulation by TGFß in fibroblast and impaired expression and function in systemic sclerosis: a novel mechanism for progressive fibrogenesis.

Wei J, Ghosh AK, Sargent JL, Komura K, Wu M, Huang QQ, Jain M, Whitfield ML, Feghali-Bostwick C, Varga J. Wei J, et al. PLoS One. 2010 Nov 2;5(11):e13778. doi: 10.1371/journal.pone.0013778. PLoS One. 2010. PMID: 21072170 Free PMC article.

8

Canonical Wnt signaling induces skin fibrosis and subcutaneous lipoatrophy: a novel mouse model for scleroderma?

Wei J, Melichian D, Komura K, Hinchcliff M, Lam AP, Lafyatis R, Gottardi CJ, MacDougald OA, Varga J. Wei J, et al. Arthritis Rheum. 2011 Jun;63(6):1707-17. doi: 10.1002/art.30312. Arthritis Rheum. 2011. PMID: 21370225 Free PMC article.

9

Nuclear β-catenin is increased in systemic sclerosis pulmonary fibrosis and promotes lung fibroblast migration and proliferation.

Lam AP, Flozak AS, Russell S, Wei J, Jain M, Mutlu GM, Budinger GR, Feghali-Bostwick CA, Varga J, Gottardi CJ. Lam AP, et al. Among authors: wei j. Am J Respir Cell Mol Biol. 2011 Nov;45(5):915-22. doi: 10.1165/rcmb.2010-0113OC. Epub 2011 Mar 31. Am J Respir Cell Mol Biol. 2011. PMID: 21454805 Free PMC article.

10

The early growth response gene Egr2 (Alias Krox20) is a novel transcriptional target of transforming growth factor-β that is up-regulated in systemic sclerosis and mediates profibrotic responses.

Fang F, Ooka K, Bhattacharyya S, Wei J, Wu M, Du P, Lin S, Del Galdo F, Feghali-Bostwick CA, Varga J. Fang F, et al. Among authors: wei j. Am J Pathol. 2011 May;178(5):2077-90. doi: 10.1016/j.ajpath.2011.01.035. Am J Pathol. 2011. PMID: 21514423 Free PMC article.

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