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The multiple facets of mTOR in immunity.
Weichhart T, Säemann MD. Weichhart T, et al. Trends Immunol. 2009 May;30(5):218-26. doi: 10.1016/j.it.2009.02.002. Epub 2009 Apr 8. Trends Immunol. 2009. PMID: 19362054 Review.
The PI3K pathway preserves metabolic health through MARCO-dependent lipid uptake by adipose tissue macrophages.
Brunner JS, Vogel A, Lercher A, Caldera M, Korosec A, Pühringer M, Hofmann M, Hajto A, Kieler M, Garrido LQ, Kerndl M, Kuttke M, Mesteri I, Górna MW, Kulik M, Dominiak PM, Brandon AE, Estevez E, Egan CL, Gruber F, Schweiger M, Menche J, Bergthaler A, Weichhart T, Klavins K, Febbraio MA, Sharif O, Schabbauer G. Brunner JS, et al. Among authors: weichhart t. Nat Metab. 2020 Dec;2(12):1427-1442. doi: 10.1038/s42255-020-00311-5. Epub 2020 Nov 16. Nat Metab. 2020. PMID: 33199895
Environmental arginine controls multinuclear giant cell metabolism and formation.
Brunner JS, Vulliard L, Hofmann M, Kieler M, Lercher A, Vogel A, Russier M, Brüggenthies JB, Kerndl M, Saferding V, Niederreiter B, Junza A, Frauenstein A, Scholtysek C, Mikami Y, Klavins K, Krönke G, Bergthaler A, O'Shea JJ, Weichhart T, Meissner F, Smolen JS, Cheng P, Yanes O, Menche J, Murray PJ, Sharif O, Blüml S, Schabbauer G. Brunner JS, et al. Among authors: weichhart t. Nat Commun. 2020 Jan 22;11(1):431. doi: 10.1038/s41467-020-14285-1. Nat Commun. 2020. PMID: 31969567 Free PMC article.
Impairment of T cell interactions with antigen-presenting cells by immunosuppressive drugs reveals involvement of calcineurin and NF-kappaB in immunological synapse formation.
Zeyda M, Geyeregger R, Poglitsch M, Weichhart T, Zlabinger GJ, Koyasu S, Hörl WH, Stulnig TM, Watschinger B, Saemann MD. Zeyda M, et al. Among authors: weichhart t. J Leukoc Biol. 2007 Jan;81(1):319-27. doi: 10.1189/jlb.0606378. Epub 2006 Oct 12. J Leukoc Biol. 2007. PMID: 17038582
The TSC-mTOR signaling pathway regulates the innate inflammatory response.
Weichhart T, Costantino G, Poglitsch M, Rosner M, Zeyda M, Stuhlmeier KM, Kolbe T, Stulnig TM, Hörl WH, Hengstschläger M, Müller M, Säemann MD. Weichhart T, et al. Immunity. 2008 Oct 17;29(4):565-77. doi: 10.1016/j.immuni.2008.08.012. Epub 2008 Oct 9. Immunity. 2008. PMID: 18848473
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