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Comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome P450 activities.
Li XQ, Andersson TB, Ahlström M, Weidolf L. Li XQ, et al. Drug Metab Dispos. 2004 Aug;32(8):821-7. doi: 10.1124/dmd.32.8.821. Drug Metab Dispos. 2004. PMID: 15258107
Stereoselective metabolism of omeprazole by human cytochrome P450 enzymes.
Abelö A, Andersson TB, Antonsson M, Naudot AK, Skånberg I, Weidolf L. Abelö A, et al. Drug Metab Dispos. 2000 Aug;28(8):966-72. Drug Metab Dispos. 2000. PMID: 10901708
Pharmacokinetic studies with esomeprazole, the (S)-isomer of omeprazole.
Andersson T, Hassan-Alin M, Hasselgren G, Röhss K, Weidolf L. Andersson T, et al. Clin Pharmacokinet. 2001;40(6):411-26. doi: 10.2165/00003088-200140060-00003. Clin Pharmacokinet. 2001. PMID: 11475467 Review.
Enantiomer/enantiomer interactions between the S- and R- isomers of omeprazole in human cytochrome P450 enzymes: major role of CYP2C19 and CYP3A4.
Li XQ, Weidolf L, Simonsson R, Andersson TB. Li XQ, et al. J Pharmacol Exp Ther. 2005 Nov;315(2):777-87. doi: 10.1124/jpet.105.090928. Epub 2005 Aug 10. J Pharmacol Exp Ther. 2005. PMID: 16093273
State-of-the-art tools for computational site of metabolism predictions: comparative analysis, mechanistical insights, and future applications.
Afzelius L, Arnby CH, Broo A, Carlsson L, Isaksson C, Jurva U, Kjellander B, Kolmodin K, Nilsson K, Raubacher F, Weidolf L. Afzelius L, et al. Drug Metab Rev. 2007;39(1):61-86. doi: 10.1080/03602530600969374. Drug Metab Rev. 2007. PMID: 17364881
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