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Effects of an Rb mutation in the mouse.
Jacks T, Fazeli A, Schmitt EM, Bronson RT, Goodell MA, Weinberg RA. Jacks T, et al. Nature. 1992 Sep 24;359(6393):295-300. doi: 10.1038/359295a0. Nature. 1992. PMID: 1406933
Tumour predisposition in mice heterozygous for a targeted mutation in Nf1.
Jacks T, Shih TS, Schmitt EM, Bronson RT, Bernards A, Weinberg RA. Jacks T, et al. Nat Genet. 1994 Jul;7(3):353-61. doi: 10.1038/ng0794-353. Nat Genet. 1994. PMID: 7920653
Cyclin D2 is an FSH-responsive gene involved in gonadal cell proliferation and oncogenesis.
Sicinski P, Donaher JL, Geng Y, Parker SB, Gardner H, Park MY, Robker RL, Richards JS, McGinnis LK, Biggers JD, Eppig JJ, Bronson RT, Elledge SJ, Weinberg RA. Sicinski P, et al. Nature. 1996 Dec 5;384(6608):470-4. doi: 10.1038/384470a0. Nature. 1996. PMID: 8945475
Creation of human tumour cells with defined genetic elements.
Hahn WC, Counter CM, Lundberg AS, Beijersbergen RL, Brooks MW, Weinberg RA. Hahn WC, et al. Nature. 1999 Jul 29;400(6743):464-8. doi: 10.1038/22780. Nature. 1999. PMID: 10440377
Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics.
Dickson MA, Hahn WC, Ino Y, Ronfard V, Wu JY, Weinberg RA, Louis DN, Li FP, Rheinwald JG. Dickson MA, et al. Mol Cell Biol. 2000 Feb;20(4):1436-47. doi: 10.1128/mcb.20.4.1436-1447.2000. Mol Cell Biol. 2000. PMID: 10648628 Free PMC article.
Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells.
Elenbaas B, Spirio L, Koerner F, Fleming MD, Zimonjic DB, Donaher JL, Popescu NC, Hahn WC, Weinberg RA. Elenbaas B, et al. Genes Dev. 2001 Jan 1;15(1):50-65. doi: 10.1101/gad.828901. Genes Dev. 2001. PMID: 11156605 Free PMC article.
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