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The genomic tag hypothesis: modern viruses as molecular fossils of ancient strategies for genomic replication, and clues regarding the origin of protein synthesis.
Weiner AM, Maizels N. Weiner AM, et al. Biol Bull. 1999 Jun;196(3):327-8; discussion 329-30. doi: 10.2307/1542962. Biol Bull. 1999. PMID: 10390830 Review. No abstract available.
Archaeal CCA-adding enzymes: central role of a highly conserved beta-turn motif in RNA polymerization without translocation.
Cho HD, Verlinde CL, Weiner AM. Cho HD, et al. Among authors: weiner am. J Biol Chem. 2005 Mar 11;280(10):9555-66. doi: 10.1074/jbc.M412594200. Epub 2004 Dec 7. J Biol Chem. 2005. PMID: 15590678
U2 small nuclear RNA is a substrate for the CCA-adding enzyme (tRNA nucleotidyltransferase).
Cho HD, Tomita K, Suzuki T, Weiner AM. Cho HD, et al. Among authors: weiner am. J Biol Chem. 2002 Feb 1;277(5):3447-55. doi: 10.1074/jbc.M109559200. Epub 2001 Nov 7. J Biol Chem. 2002. PMID: 11700323
Closely related CC- and A-adding enzymes collaborate to construct and repair the 3'-terminal CCA of tRNA in Synechocystis sp. and Deinococcus radiodurans.
Tomita K, Weiner AM. Tomita K, et al. Among authors: weiner am. J Biol Chem. 2002 Dec 13;277(50):48192-8. doi: 10.1074/jbc.M207527200. Epub 2002 Oct 4. J Biol Chem. 2002. PMID: 12370185
A model for C74 addition by CCA-adding enzymes: C74 addition, like C75 and A76 addition, does not involve tRNA translocation.
Cho HD, Chen Y, Varani G, Weiner AM. Cho HD, et al. Among authors: weiner am. J Biol Chem. 2006 Apr 7;281(14):9801-11. doi: 10.1074/jbc.M512603200. Epub 2006 Feb 1. J Biol Chem. 2006. PMID: 16455665
Crystal structures of an archaeal class I CCA-adding enzyme and its nucleotide complexes.
Xiong Y, Li F, Wang J, Weiner AM, Steitz TA. Xiong Y, et al. Among authors: weiner am. Mol Cell. 2003 Nov;12(5):1165-72. doi: 10.1016/s1097-2765(03)00440-4. Mol Cell. 2003. PMID: 14636575
A single catalytically active subunit in the multimeric Sulfolobus shibatae CCA-adding enzyme can carry out all three steps of CCA addition.
Cho HD, Weiner AM. Cho HD, et al. Among authors: weiner am. J Biol Chem. 2004 Sep 17;279(38):40130-6. doi: 10.1074/jbc.M405518200. Epub 2004 Jul 19. J Biol Chem. 2004. PMID: 15265870
Concerted evolution of the tandemly repeated genes encoding human U2 snRNA (the RNU2 locus) involves rapid intrachromosomal homogenization and rare interchromosomal gene conversion.
Liao D, Pavelitz T, Kidd JR, Kidd KK, Weiner AM. Liao D, et al. Among authors: weiner am. EMBO J. 1997 Feb 3;16(3):588-98. doi: 10.1093/emboj/16.3.588. EMBO J. 1997. PMID: 9034341 Free PMC article.
Concerted evolution of the tandemly repeated genes encoding primate U2 small nuclear RNA (the RNU2 locus) does not prevent rapid diversification of the (CT)n.(GA)n microsatellite embedded within the U2 repeat unit.
Liao D, Weiner AM. Liao D, et al. Among authors: weiner am. Genomics. 1995 Dec 10;30(3):583-93. doi: 10.1006/geno.1995.1280. Genomics. 1995. PMID: 8825646
CCA-adding enzymes and poly(A) polymerases are all members of the same nucleotidyltransferase superfamily: characterization of the CCA-adding enzyme from the archaeal hyperthermophile Sulfolobus shibatae.
Yue D, Maizels N, Weiner AM. Yue D, et al. Among authors: weiner am. RNA. 1996 Sep;2(9):895-908. RNA. 1996. PMID: 8809016 Free PMC article.
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