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Page 1
Intrinsic efficacy of antipsychotics at human D2, D3, and D4 dopamine receptors: identification of the clozapine metabolite N-desmethylclozapine as a D2/D3 partial agonist.
Burstein ES, Ma J, Wong S, Gao Y, Pham E, Knapp AE, Nash NR, Olsson R, Davis RE, Hacksell U, Weiner DM, Brann MR. Burstein ES, et al. Among authors: weiner dm. J Pharmacol Exp Ther. 2005 Dec;315(3):1278-87. doi: 10.1124/jpet.105.092155. Epub 2005 Aug 31. J Pharmacol Exp Ther. 2005. PMID: 16135699
Pharmacological characterization of AC-90179 [2-(4-methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide hydrochloride]: a selective serotonin 2A receptor inverse agonist.
Vanover KE, Harvey SC, Son T, Bradley SR, Kold H, Makhay M, Veinbergs I, Spalding TA, Weiner DM, Andersson CM, Tolf BR, Brann MR, Hacksell U, Davis RE. Vanover KE, et al. Among authors: weiner dm. J Pharmacol Exp Ther. 2004 Sep;310(3):943-51. doi: 10.1124/jpet.104.066688. Epub 2004 Apr 21. J Pharmacol Exp Ther. 2004. PMID: 15102927
Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine(2A) receptor inverse agonist.
Vanover KE, Weiner DM, Makhay M, Veinbergs I, Gardell LR, Lameh J, Del Tredici AL, Piu F, Schiffer HH, Ott TR, Burstein ES, Uldam AK, Thygesen MB, Schlienger N, Andersson CM, Son TY, Harvey SC, Powell SB, Geyer MA, Tolf BR, Brann MR, Davis RE. Vanover KE, et al. Among authors: weiner dm. J Pharmacol Exp Ther. 2006 May;317(2):910-8. doi: 10.1124/jpet.105.097006. Epub 2006 Feb 9. J Pharmacol Exp Ther. 2006. PMID: 16469866
Pharmacology of N-desmethylclozapine.
Lameh J, Burstein ES, Taylor E, Weiner DM, Vanover KE, Bonhaus DW. Lameh J, et al. Among authors: weiner dm. Pharmacol Ther. 2007 Aug;115(2):223-31. doi: 10.1016/j.pharmthera.2007.05.004. Epub 2007 May 21. Pharmacol Ther. 2007. PMID: 17583355 Review.
5-hydroxytryptamine2A receptor inverse agonists as antipsychotics.
Weiner DM, Burstein ES, Nash N, Croston GE, Currier EA, Vanover KE, Harvey SC, Donohue E, Hansen HC, Andersson CM, Spalding TA, Gibson DF, Krebs-Thomson K, Powell SB, Geyer MA, Hacksell U, Brann MR. Weiner DM, et al. J Pharmacol Exp Ther. 2001 Oct;299(1):268-76. J Pharmacol Exp Ther. 2001. PMID: 11561089
The role of M1 muscarinic receptor agonism of N-desmethylclozapine in the unique clinical effects of clozapine.
Weiner DM, Meltzer HY, Veinbergs I, Donohue EM, Spalding TA, Smith TT, Mohell N, Harvey SC, Lameh J, Nash N, Vanover KE, Olsson R, Jayathilake K, Lee M, Levey AI, Hacksell U, Burstein ES, Davis RE, Brann MR. Weiner DM, et al. Psychopharmacology (Berl). 2004 Dec;177(1-2):207-16. doi: 10.1007/s00213-004-1940-5. Epub 2004 Jul 16. Psychopharmacology (Berl). 2004. PMID: 15258717
Pharmacology of polymorphic variants of the human 5-HT1A receptor.
Del Tredici AL, Schiffer HH, Burstein ES, Lameh J, Mohell N, Hacksell U, Brann MR, Weiner DM. Del Tredici AL, et al. Among authors: weiner dm. Biochem Pharmacol. 2004 Feb 1;67(3):479-90. doi: 10.1016/j.bcp.2003.09.030. Biochem Pharmacol. 2004. PMID: 15037200
83 results