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Phase 3 Study of Ibalizumab for Multidrug-Resistant HIV-1.
Emu B, Fessel J, Schrader S, Kumar P, Richmond G, Win S, Weinheimer S, Marsolais C, Lewis S. Emu B, et al. Among authors: weinheimer s. N Engl J Med. 2018 Aug 16;379(7):645-654. doi: 10.1056/NEJMoa1711460. N Engl J Med. 2018. PMID: 30110589 Free article. Clinical Trial.
Safety, pharmacokinetics, and antiretroviral activity of multiple doses of ibalizumab (formerly TNX-355), an anti-CD4 monoclonal antibody, in human immunodeficiency virus type 1-infected adults.
Jacobson JM, Kuritzkes DR, Godofsky E, DeJesus E, Larson JA, Weinheimer SP, Lewis ST. Jacobson JM, et al. Among authors: weinheimer sp. Antimicrob Agents Chemother. 2009 Feb;53(2):450-7. doi: 10.1128/AAC.00942-08. Epub 2008 Nov 17. Antimicrob Agents Chemother. 2009. PMID: 19015347 Free PMC article. Clinical Trial.
The efficacy of an anti-CD4 monoclonal antibody for HIV-1 treatment.
Fessel WJ, Anderson B, Follansbee SE, Winters MA, Lewis ST, Weinheimer SP, Petropoulos CJ, Shafer RW. Fessel WJ, et al. Among authors: weinheimer sp. Antiviral Res. 2011 Dec;92(3):484-7. doi: 10.1016/j.antiviral.2011.09.010. Epub 2011 Oct 4. Antiviral Res. 2011. PMID: 22001594 Free PMC article.
Ibalizumab shows in-vitro activity against group A and group B HIV-2 clinical isolates.
Le Hingrat Q, Collin G, Bachelard A, Ghosn J, Chalal S, Pacanowski J, Peytavin G, Weinheimer S, Marsolais C, Damond F, Matheron S, Charpentier C, Descamps D; ANRS CO5 HIV-2 cohort. Le Hingrat Q, et al. Among authors: weinheimer s. AIDS. 2022 Jul 1;36(8):1055-1060. doi: 10.1097/QAD.0000000000003218. Epub 2022 Mar 7. AIDS. 2022. PMID: 35262531
Clinical emergence of entecavir-resistant hepatitis B virus requires additional substitutions in virus already resistant to Lamivudine.
Tenney DJ, Levine SM, Rose RE, Walsh AW, Weinheimer SP, Discotto L, Plym M, Pokornowski K, Yu CF, Angus P, Ayres A, Bartholomeusz A, Sievert W, Thompson G, Warner N, Locarnini S, Colonno RJ. Tenney DJ, et al. Among authors: weinheimer sp. Antimicrob Agents Chemother. 2004 Sep;48(9):3498-507. doi: 10.1128/AAC.48.9.3498-3507.2004. Antimicrob Agents Chemother. 2004. PMID: 15328117 Free PMC article.
32 results