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Rapid evolutionary escape by large populations from local fitness peaks is likely in nature.
Weinreich DM, Chao L. Weinreich DM, et al. Evolution. 2005 Jun;59(6):1175-82. Evolution. 2005. PMID: 16050095
The rates of molecular evolution in rodent and primate mitochondrial DNA.
Weinreich DM. Weinreich DM. J Mol Evol. 2001 Jan;52(1):40-50. doi: 10.1007/s002390010132. J Mol Evol. 2001. PMID: 11139293
The age of nonsynonymous and synonymous mutations in animal mtDNA and implications for the mildly deleterious theory.
Nielsen R, Weinreich DM. Nielsen R, et al. Among authors: weinreich dm. Genetics. 1999 Sep;153(1):497-506. Genetics. 1999. PMID: 10471729 Free PMC article.
Contrasting patterns of nonneutral evolution in proteins encoded in nuclear and mitochondrial genomes.
Weinreich DM, Rand DM. Weinreich DM, et al. Genetics. 2000 Sep;156(1):385-99. Genetics. 2000. PMID: 10978302 Free PMC article.
Measuring epistasis in fitness landscapes: The correlation of fitness effects of mutations.
Ferretti L, Schmiegelt B, Weinreich D, Yamauchi A, Kobayashi Y, Tajima F, Achaz G. Ferretti L, et al. J Theor Biol. 2016 May 7;396:132-43. doi: 10.1016/j.jtbi.2016.01.037. Epub 2016 Feb 20. J Theor Biol. 2016. PMID: 26854875
Adaptive Landscape by Environment Interactions Dictate Evolutionary Dynamics in Models of Drug Resistance.
Ogbunugafor CB, Wylie CS, Diakite I, Weinreich DM, Hartl DL. Ogbunugafor CB, et al. Among authors: weinreich dm. PLoS Comput Biol. 2016 Jan 25;12(1):e1004710. doi: 10.1371/journal.pcbi.1004710. eCollection 2016 Jan. PLoS Comput Biol. 2016. PMID: 26808374 Free PMC article.
Mutational reversions during adaptive protein evolution.
DePristo MA, Hartl DL, Weinreich DM. DePristo MA, et al. Among authors: weinreich dm. Mol Biol Evol. 2007 Aug;24(8):1608-10. doi: 10.1093/molbev/msm118. Epub 2007 Jun 7. Mol Biol Evol. 2007. PMID: 17556755
Patterns and mechanisms of genetic and phenotypic differentiation in marine microbes.
Polz MF, Hunt DE, Preheim SP, Weinreich DM. Polz MF, et al. Among authors: weinreich dm. Philos Trans R Soc Lond B Biol Sci. 2006 Nov 29;361(1475):2009-21. doi: 10.1098/rstb.2006.1928. Philos Trans R Soc Lond B Biol Sci. 2006. PMID: 17062417 Free PMC article. Review.
Darwinian evolution can follow only very few mutational paths to fitter proteins.
Weinreich DM, Delaney NF, Depristo MA, Hartl DL. Weinreich DM, et al. Science. 2006 Apr 7;312(5770):111-4. doi: 10.1126/science.1123539. Science. 2006. PMID: 16601193
The rank ordering of genotypic fitness values predicts genetic constraint on natural selection on landscapes lacking sign epistasis.
Weinreich DM. Weinreich DM. Genetics. 2005 Nov;171(3):1397-405. doi: 10.1534/genetics.104.036830. Epub 2005 Aug 3. Genetics. 2005. PMID: 16079241 Free PMC article.
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