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CCN3/NOV small interfering RNA enhances fibrogenic gene expression in primary hepatic stellate cells and cirrhotic fat storing cell line CFSC.
Borkham-Kamphorst E, van Roeyen CR, Van de Leur E, Floege J, Weiskirchen R. Borkham-Kamphorst E, et al. J Cell Commun Signal. 2012 Mar;6(1):11-25. doi: 10.1007/s12079-011-0141-3. Epub 2011 Jul 5. J Cell Commun Signal. 2012. PMID: 21748432 Free PMC article.
Comparative evaluation of gene delivery devices in primary cultures of rat hepatic stellate cells and rat myofibroblasts.
Weiskirchen R, Kneifel J, Weiskirchen S, van de Leur E, Kunz D, Gressner AM. Weiskirchen R, et al. BMC Cell Biol. 2000;1:4. doi: 10.1186/1471-2121-1-4. Epub 2000 Dec 19. BMC Cell Biol. 2000. PMID: 11178102 Free PMC article.
LIM-domain protein cysteine- and glycine-rich protein 2 (CRP2) is a novel marker of hepatic stellate cells and binding partner of the protein inhibitor of activated STAT1.
Weiskirchen R, Moser M, Weiskirchen S, Erdel M, Dahmen S, Buettner R, Gressner AM. Weiskirchen R, et al. Biochem J. 2001 Nov 1;359(Pt 3):485-96. doi: 10.1042/0264-6021:3590485. Biochem J. 2001. PMID: 11672422 Free PMC article.
Roles of TGF-beta in hepatic fibrosis.
Gressner AM, Weiskirchen R, Breitkopf K, Dooley S. Gressner AM, et al. Front Biosci. 2002 Apr 1;7:d793-807. Front Biosci. 2002. PMID: 11897555 Review.
Adenoviral delivery of an antisense RNA complementary to the 3' coding sequence of transforming growth factor-beta1 inhibits fibrogenic activities of hepatic stellate cells.
Arias M, Lahme B, Van de Leur E, Gressner AM, Weiskirchen R. Arias M, et al. Cell Growth Differ. 2002 Jun;13(6):265-73. Cell Growth Differ. 2002. PMID: 12114216
Adenoviral expression of a transforming growth factor-beta1 antisense mRNA is effective in preventing liver fibrosis in bile-duct ligated rats.
Arias M, Sauer-Lehnen S, Treptau J, Janoschek N, Theuerkauf I, Buettner R, Gressner AM, Weiskirchen R. Arias M, et al. BMC Gastroenterol. 2003 Oct 18;3:29. doi: 10.1186/1471-230X-3-29. BMC Gastroenterol. 2003. PMID: 14565855 Free PMC article.
Induction of cell death in activated hepatic stellate cells by targeted gene expression of the thymidine kinase/ganciclovir system.
Janoschek N, van de Leur E, Gressner AM, Weiskirchen R. Janoschek N, et al. Biochem Biophys Res Commun. 2004 Apr 16;316(4):1107-15. doi: 10.1016/j.bbrc.2004.02.147. Biochem Biophys Res Commun. 2004. PMID: 15044099
Inhibitory effect of soluble PDGF-beta receptor in culture-activated hepatic stellate cells.
Borkham-Kamphorst E, Stoll D, Gressner AM, Weiskirchen R. Borkham-Kamphorst E, et al. Biochem Biophys Res Commun. 2004 Apr 30;317(2):451-62. doi: 10.1016/j.bbrc.2004.03.064. Biochem Biophys Res Commun. 2004. PMID: 15063779
Dominant-negative soluble PDGF-beta receptor inhibits hepatic stellate cell activation and attenuates liver fibrosis.
Borkham-Kamphorst E, Herrmann J, Stoll D, Treptau J, Gressner AM, Weiskirchen R. Borkham-Kamphorst E, et al. Lab Invest. 2004 Jun;84(6):766-77. doi: 10.1038/labinvest.3700094. Lab Invest. 2004. PMID: 15077122
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