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Targets for antiinflammatory drugs.
Cronstein BN, Weissmann G. Cronstein BN, et al. Annu Rev Pharmacol Toxicol. 1995;35:449-62. doi: 10.1146/annurev.pa.35.040195.002313. Annu Rev Pharmacol Toxicol. 1995. PMID: 7598502 Review.
Salicylates and sulfasalazine, but not glucocorticoids, inhibit leukocyte accumulation by an adenosine-dependent mechanism that is independent of inhibition of prostaglandin synthesis and p105 of NFkappaB.
Cronstein BN, Montesinos MC, Weissmann G. Cronstein BN, et al. Proc Natl Acad Sci U S A. 1999 May 25;96(11):6377-81. doi: 10.1073/pnas.96.11.6377. Proc Natl Acad Sci U S A. 1999. PMID: 10339595 Free PMC article.
Modes of action of aspirin-like drugs: salicylates inhibit erk activation and integrin-dependent neutrophil adhesion.
Pillinger MH, Capodici C, Rosenthal P, Kheterpal N, Hanft S, Philips MR, Weissmann G. Pillinger MH, et al. Proc Natl Acad Sci U S A. 1998 Nov 24;95(24):14540-5. doi: 10.1073/pnas.95.24.14540. Proc Natl Acad Sci U S A. 1998. PMID: 9826736 Free PMC article.
The mode of action of aspirin-like drugs: effect on inducible nitric oxide synthase.
Amin AR, Vyas P, Attur M, Leszczynska-Piziak J, Patel IR, Weissmann G, Abramson SB. Amin AR, et al. Proc Natl Acad Sci U S A. 1995 Aug 15;92(17):7926-30. doi: 10.1073/pnas.92.17.7926. Proc Natl Acad Sci U S A. 1995. PMID: 7544010 Free PMC article.
Sites of action for future therapy: an adenosine-dependent mechanism by which aspirin retains its antiinflammatory activity in cyclooxygenase-2 and NFkappaB knockout mice.
Cronstein BN, Montesinos MC, Weissmann G. Cronstein BN, et al. Osteoarthritis Cartilage. 1999 Jul;7(4):361-3. doi: 10.1053/joca.1998.0236. Osteoarthritis Cartilage. 1999. PMID: 10419767
Reiter's syndrome among Asian shipboard immigrants: the case of The Golden Venture.
Solitar BM, Lozada CJ, Tseng CE, Lowe AM, Krajewski WM, Blanchard K, Pillinger M, Weissmann G. Solitar BM, et al. Semin Arthritis Rheum. 1998 Apr;27(5):293-300. doi: 10.1016/s0049-0172(98)80050-4. Semin Arthritis Rheum. 1998. PMID: 9572711
The actions of NSAIDs.
Weissmann G. Weissmann G. Hosp Pract (Off Ed). 1991 Aug 15;26(8):60-8, 71-2, 75-6. doi: 10.1080/21548331.1991.11705279. Hosp Pract (Off Ed). 1991. PMID: 1907978
Inhibition of neutrophil function by aspirin-like drugs (NSAIDS): requirement for assembly of heterotrimeric G proteins in bilayer phospholipid.
Abramson SB, Leszczynska-Piziak J, Clancy RM, Philips M, Weissmann G. Abramson SB, et al. Biochem Pharmacol. 1994 Feb 9;47(3):563-72. doi: 10.1016/0006-2952(94)90189-9. Biochem Pharmacol. 1994. PMID: 8117325
We examined the effects of sodium salicylate and piroxicam on GTP/GDP exchange by a regulatory G protein (G alpha i). Plasma membrane and cytosol of human neutrophils were prepared by nitrogen cavitation and discontinuous sucrose density centrifugation. ...Membrane- …
We examined the effects of sodium salicylate and piroxicam on GTP/GDP exchange by a regulatory G protein (G alpha i). Plasma m …
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