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Fc-optimized CD40 agonistic antibody elicits tertiary lymphoid structure formation and systemic antitumor immunity in metastatic cancer.
Osorio JC, Knorr DA, Weitzenfeld P, Blanchard L, Yao N, Baez M, Sevilla C, DiLillo M, Rahman J, Sharma VP, Bromberg J, Postow MA, Ariyan C, Robson ME, Ravetch JV. Osorio JC, et al. Among authors: weitzenfeld p. Cancer Cell. 2025 Oct 13;43(10):1902-1916.e9. doi: 10.1016/j.ccell.2025.07.013. Epub 2025 Aug 14. Cancer Cell. 2025. PMID: 40816292 Free PMC article. Clinical Trial.