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Inflammation, stress, and diabetes.
Wellen KE, Hotamisligil GS. Wellen KE, et al. J Clin Invest. 2005 May;115(5):1111-9. doi: 10.1172/JCI25102. J Clin Invest. 2005. PMID: 15864338 Free PMC article. Review.
Coordinated regulation of nutrient and inflammatory responses by STAMP2 is essential for metabolic homeostasis.
Wellen KE, Fucho R, Gregor MF, Furuhashi M, Morgan C, Lindstad T, Vaillancourt E, Gorgun CZ, Saatcioglu F, Hotamisligil GS. Wellen KE, et al. Cell. 2007 May 4;129(3):537-48. doi: 10.1016/j.cell.2007.02.049. Cell. 2007. PMID: 17482547 Free PMC article.
Obesity-induced inflammatory changes in adipose tissue.
Wellen KE, Hotamisligil GS. Wellen KE, et al. J Clin Invest. 2003 Dec;112(12):1785-8. doi: 10.1172/JCI20514. J Clin Invest. 2003. PMID: 14679172 Free PMC article.
Dysregulated metabolism contributes to oncogenesis.
Hirschey MD, DeBerardinis RJ, Diehl AME, Drew JE, Frezza C, Green MF, Jones LW, Ko YH, Le A, Lea MA, Locasale JW, Longo VD, Lyssiotis CA, McDonnell E, Mehrmohamadi M, Michelotti G, Muralidhar V, Murphy MP, Pedersen PL, Poore B, Raffaghello L, Rathmell JC, Sivanand S, Vander Heiden MG, Wellen KE; Target Validation Team. Hirschey MD, et al. Semin Cancer Biol. 2015 Dec;35 Suppl:S129-S150. doi: 10.1016/j.semcancer.2015.10.002. Epub 2015 Oct 8. Semin Cancer Biol. 2015. PMID: 26454069 Free PMC article. Review.
ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch.
Zhao S, Torres A, Henry RA, Trefely S, Wallace M, Lee JV, Carrer A, Sengupta A, Campbell SL, Kuo YM, Frey AJ, Meurs N, Viola JM, Blair IA, Weljie AM, Metallo CM, Snyder NW, Andrews AJ, Wellen KE. Zhao S, et al. Cell Rep. 2016 Oct 18;17(4):1037-1052. doi: 10.1016/j.celrep.2016.09.069. Cell Rep. 2016. PMID: 27760311 Free PMC article.
Metabolic Signaling to the Nucleus in Cancer.
Campbell SL, Wellen KE. Campbell SL, et al. Mol Cell. 2018 Aug 2;71(3):398-408. doi: 10.1016/j.molcel.2018.07.015. Mol Cell. 2018. PMID: 30075141 Review.
Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation.
Lee JV, Carrer A, Shah S, Snyder NW, Wei S, Venneti S, Worth AJ, Yuan ZF, Lim HW, Liu S, Jackson E, Aiello NM, Haas NB, Rebbeck TR, Judkins A, Won KJ, Chodosh LA, Garcia BA, Stanger BZ, Feldman MD, Blair IA, Wellen KE. Lee JV, et al. Cell Metab. 2014 Aug 5;20(2):306-319. doi: 10.1016/j.cmet.2014.06.004. Epub 2014 Jul 3. Cell Metab. 2014. PMID: 24998913 Free PMC article.
Adipocyte ACLY Facilitates Dietary Carbohydrate Handling to Maintain Metabolic Homeostasis in Females.
Fernandez S, Viola JM, Torres A, Wallace M, Trefely S, Zhao S, Affronti HC, Gengatharan JM, Guertin DA, Snyder NW, Metallo CM, Wellen KE. Fernandez S, et al. Cell Rep. 2019 May 28;27(9):2772-2784.e6. doi: 10.1016/j.celrep.2019.04.112. Cell Rep. 2019. PMID: 31141698 Free PMC article.
Metabolic reprogramming in cancer: unraveling the role of glutamine in tumorigenesis.
Daye D, Wellen KE. Daye D, et al. Semin Cell Dev Biol. 2012 Jun;23(4):362-9. doi: 10.1016/j.semcdb.2012.02.002. Epub 2012 Feb 11. Semin Cell Dev Biol. 2012. PMID: 22349059 Review.
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