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14 results
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Islet beta cell expression of constitutively active Akt1/PKB alpha induces striking hypertrophy, hyperplasia, and hyperinsulinemia.
Bernal-Mizrachi E, Wen W, Stahlhut S, Welling CM, Permutt MA. Bernal-Mizrachi E, et al. Among authors: welling cm. J Clin Invest. 2001 Dec;108(11):1631-8. doi: 10.1172/JCI13785. J Clin Invest. 2001. PMID: 11733558 Free PMC article.
Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance.
Tanabe K, Liu Z, Patel S, Doble BW, Li L, Cras-Méneur C, Martinez SC, Welling CM, White MF, Bernal-Mizrachi E, Woodgett JR, Permutt MA. Tanabe K, et al. Among authors: welling cm. PLoS Biol. 2008 Feb;6(2):e37. doi: 10.1371/journal.pbio.0060037. PLoS Biol. 2008. PMID: 18288891 Free PMC article.
Glucose and fatty acids synergize to promote B-cell apoptosis through activation of glycogen synthase kinase 3β independent of JNK activation.
Tanabe K, Liu Y, Hasan SD, Martinez SC, Cras-Méneur C, Welling CM, Bernal-Mizrachi E, Tanizawa Y, Rhodes CJ, Zmuda E, Hai T, Abumrad NA, Permutt MA. Tanabe K, et al. Among authors: welling cm. PLoS One. 2011 Apr 26;6(4):e18146. doi: 10.1371/journal.pone.0018146. PLoS One. 2011. PMID: 21541314 Free PMC article.
Mice conditionally lacking the Wolfram gene in pancreatic islet beta cells exhibit diabetes as a result of enhanced endoplasmic reticulum stress and apoptosis.
Riggs AC, Bernal-Mizrachi E, Ohsugi M, Wasson J, Fatrai S, Welling C, Murray J, Schmidt RE, Herrera PL, Permutt MA. Riggs AC, et al. Diabetologia. 2005 Nov;48(11):2313-21. doi: 10.1007/s00125-005-1947-4. Epub 2005 Oct 8. Diabetologia. 2005. PMID: 16215705
A variant insulin promoter in non-insulin-dependent diabetes mellitus.
Olansky L, Welling C, Giddings S, Adler S, Bourey R, Dowse G, Serjeantson S, Zimmet P, Permutt MA. Olansky L, et al. J Clin Invest. 1992 May;89(5):1596-602. doi: 10.1172/JCI115754. J Clin Invest. 1992. PMID: 1569197 Free PMC article.
Isolation and characterization of the human AKT1 gene, identification of 13 single nucleotide polymorphisms (SNPs), and their lack of association with Type II diabetes.
Matsubara A, Wasson JC, Donelan SS, Welling CM, Glaser B, Permutt MA. Matsubara A, et al. Among authors: welling cm. Diabetologia. 2001 Jul;44(7):910-3. doi: 10.1007/s001250100577. Diabetologia. 2001. PMID: 11508278
Sequence variants in the sulfonylurea receptor (SUR) gene are associated with NIDDM in Caucasians.
Inoue H, Ferrer J, Welling CM, Elbein SC, Hoffman M, Mayorga R, Warren-Perry M, Zhang Y, Millns H, Turner R, Province M, Bryan J, Permutt MA, Aguilar-Bryan L. Inoue H, et al. Among authors: welling cm. Diabetes. 1996 Jun;45(6):825-31. doi: 10.2337/diab.45.6.825. Diabetes. 1996. PMID: 8635661
Human islet glucokinase gene. Isolation and sequence analysis of full-length cDNA.
Koranyi LI, Tanizawa Y, Welling CM, Rabin DU, Permutt MA. Koranyi LI, et al. Among authors: welling cm. Diabetes. 1992 Jul;41(7):807-11. doi: 10.2337/diab.41.7.807. Diabetes. 1992. PMID: 1612194
Variability of the insulin gene in American blacks with NIDDM. Analysis by single-strand conformational polymorphisms.
Olansky L, Janssen R, Welling C, Permutt MA. Olansky L, et al. Diabetes. 1992 Jun;41(6):742-9. doi: 10.2337/diab.41.6.742. Diabetes. 1992. PMID: 1350258
Human cholecystokinin type A receptor gene: cytogenetic localization, physical mapping, and identification of two missense variants in patients with obesity and non-insulin-dependent diabetes mellitus (NIDDM).
Inoue H, Iannotti CA, Welling CM, Veile R, Donis-Keller H, Permutt MA. Inoue H, et al. Among authors: welling cm. Genomics. 1997 Jun 1;42(2):331-5. doi: 10.1006/geno.1997.4749. Genomics. 1997. PMID: 9192855
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