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Directional motility induced by epidermal growth factor requires Cdc42.
Chou J, Burke NA, Iwabu A, Watkins SC, Wells A. Chou J, et al. Among authors: wells a. Exp Cell Res. 2003 Jul 1;287(1):47-56. doi: 10.1016/s0014-4827(03)00119-8. Exp Cell Res. 2003. PMID: 12799181
A negative feedback loop attenuates EGF-induced morphological changes.
Welsh JB, Gill GN, Rosenfeld MG, Wells A. Welsh JB, et al. Among authors: wells a. J Cell Biol. 1991 Aug;114(3):533-43. doi: 10.1083/jcb.114.3.533. J Cell Biol. 1991. PMID: 1860884 Free PMC article.
Ligand-induced transformation by a noninternalizing epidermal growth factor receptor.
Wells A, Welsh JB, Lazar CS, Wiley HS, Gill GN, Rosenfeld MG. Wells A, et al. Science. 1990 Feb 23;247(4945):962-4. doi: 10.1126/science.2305263. Science. 1990. PMID: 2305263
Epidermal growth factor (EGF) receptor carboxy-terminal domains are required for EGF-induced glucose transport in transgenic 3T3-L1 adipocytes.
Hardy RW, Gupta KB, McDonald JM, Williford J, Wells A. Hardy RW, et al. Among authors: wells a. Endocrinology. 1995 Feb;136(2):431-9. doi: 10.1210/endo.136.2.7835273. Endocrinology. 1995. PMID: 7835273
Epidermal growth factor receptor-mediated cell motility: phospholipase C activity is required, but mitogen-activated protein kinase activity is not sufficient for induced cell movement.
Chen P, Xie H, Sekar MC, Gupta K, Wells A. Chen P, et al. Among authors: wells a. J Cell Biol. 1994 Nov;127(3):847-57. doi: 10.1083/jcb.127.3.847. J Cell Biol. 1994. PMID: 7962064 Free PMC article.
We recently have demonstrated that EGF receptor (EGFR)-induced cell motility requires receptor kinase activity and autophosphorylation (P. Chen, K. Gupta, and A. Wells. 1994. J. Cell Biol. 124:547-555). This suggests that the immediate downstream effector molecule c …
We recently have demonstrated that EGF receptor (EGFR)-induced cell motility requires receptor kinase activity and autophosphorylation (P. C …
Cell movement elicited by epidermal growth factor receptor requires kinase and autophosphorylation but is separable from mitogenesis.
Chen P, Gupta K, Wells A. Chen P, et al. Among authors: wells a. J Cell Biol. 1994 Feb;124(4):547-55. doi: 10.1083/jcb.124.4.547. J Cell Biol. 1994. PMID: 8106552 Free PMC article.
Epidermal growth factor modulates cell attachment to hyaluronic acid by the cell surface glycoprotein CD44.
Zhang M, Singh RK, Wang MH, Wells A, Siegal GP. Zhang M, et al. Among authors: wells a. Clin Exp Metastasis. 1996 May;14(3):268-76. doi: 10.1007/BF00053900. Clin Exp Metastasis. 1996. PMID: 8674281
A role for gelsolin in actuating epidermal growth factor receptor-mediated cell motility.
Chen P, Murphy-Ullrich JE, Wells A. Chen P, et al. Among authors: wells a. J Cell Biol. 1996 Aug;134(3):689-98. doi: 10.1083/jcb.134.3.689. J Cell Biol. 1996. PMID: 8707848 Free PMC article.
Phospholipase C-gamma (PLC gamma) is required for EGF-induced motility (Chen, P., H. Xie, M.C. Sekar, K.B. Gupta, and A. Wells. J. Cell Biol. 1994. 127:847-857); however, the molecular basis of how PLC gamma modulates the actin filament network underlying cell motil …
Phospholipase C-gamma (PLC gamma) is required for EGF-induced motility (Chen, P., H. Xie, M.C. Sekar, K.B. Gupta, and A. Wells
Mitogenic signaling from the egf receptor is attenuated by a phospholipase C-gamma/protein kinase C feedback mechanism.
Chen P, Xie H, Wells A. Chen P, et al. Among authors: wells a. Mol Biol Cell. 1996 Jun;7(6):871-81. doi: 10.1091/mbc.7.6.871. Mol Biol Cell. 1996. PMID: 8816994 Free PMC article.
Epidermal growth factor induces glucose storage in transgenic 3T3-L1 adipocytes overexpressing epidermal growth factor receptors.
Van Epps-Fung M, Hardy RW, Williford J, Gupta K, Wells A. Van Epps-Fung M, et al. Among authors: wells a. Diabetes. 1996 Nov;45(11):1619-25. doi: 10.2337/diab.45.11.1619. Diabetes. 1996. PMID: 8866569
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