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Signalling to cancer cell invasion through PAK family kinases.

Whale A, Hashim FN, Fram S, Jones GE, Wells CM. Whale A, et al. Among authors: wells cm. Front Biosci (Landmark Ed). 2011 Jan 1;16(3):849-64. doi: 10.2741/3724. Front Biosci (Landmark Ed). 2011. PMID: 21196207 Review.

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Rho family GTPases are activated during HGF-stimulated prostate cancer-cell scattering.

Wells CM, Ahmed T, Masters JR, Jones GE. Wells CM, et al. Cell Motil Cytoskeleton. 2005 Nov;62(3):180-94. doi: 10.1002/cm.20095. Cell Motil Cytoskeleton. 2005. PMID: 16211585

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A PAK4-LIMK1 pathway drives prostate cancer cell migration downstream of HGF.

Ahmed T, Shea K, Masters JR, Jones GE, Wells CM. Ahmed T, et al. Among authors: wells cm. Cell Signal. 2008 Jul;20(7):1320-8. doi: 10.1016/j.cellsig.2008.02.021. Epub 2008 Mar 12. Cell Signal. 2008. PMID: 18424072

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ROCK1 and LIMK2 interact in spread but not blebbing cancer cells.

Shea KF, Wells CM, Garner AP, Jones GE. Shea KF, et al. Among authors: wells cm. PLoS One. 2008;3(10):e3398. doi: 10.1371/journal.pone.0003398. Epub 2008 Oct 14. PLoS One. 2008. PMID: 18852895 Free PMC article.

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The emerging importance of group II PAKs.

Wells CM, Jones GE. Wells CM, et al. Biochem J. 2010 Jan 15;425(3):465-73. doi: 10.1042/BJ20091173. Biochem J. 2010. PMID: 20070256 Review.

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PAK4: a pluripotent kinase that regulates prostate cancer cell adhesion.

Wells CM, Whale AD, Parsons M, Masters JR, Jones GE. Wells CM, et al. J Cell Sci. 2010 May 15;123(Pt 10):1663-73. doi: 10.1242/jcs.055707. Epub 2010 Apr 20. J Cell Sci. 2010. PMID: 20406887 Free PMC article.

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HGF-induced DU145 cell scatter assay.

Fram ST, Wells CM, Jones GE. Fram ST, et al. Among authors: wells cm. Methods Mol Biol. 2011;769:31-40. doi: 10.1007/978-1-61779-207-6_3. Methods Mol Biol. 2011. PMID: 21748667

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PAK4 kinase activity and somatic mutation promote carcinoma cell motility and influence inhibitor sensitivity.

Whale AD, Dart A, Holt M, Jones GE, Wells CM. Whale AD, et al. Among authors: wells cm. Oncogene. 2013 Apr 18;32(16):2114-20. doi: 10.1038/onc.2012.233. Epub 2012 Jun 11. Oncogene. 2013. PMID: 22689056 Free PMC article.

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Imaging haematopoietic cells recruitment to an acute wound in vivo identifies a role for c-Met signalling.

Falenta K, Rodaway A, Jones GE, Wells CM. Falenta K, et al. Among authors: wells cm. J Microsc. 2013 Jun;250(3):200-9. doi: 10.1111/jmi.12035. Epub 2013 Apr 12. J Microsc. 2013. PMID: 23581253

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P21-activated kinase 4--not just one of the PAK.

Dart AE, Wells CM. Dart AE, et al. Among authors: wells cm. Eur J Cell Biol. 2013 Apr-May;92(4-5):129-38. doi: 10.1016/j.ejcb.2013.03.002. Epub 2013 Apr 4. Eur J Cell Biol. 2013. PMID: 23642861 Review.

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