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A chimera between platelet-derived growth factor beta-receptor and fibroblast growth factor receptor-1 stimulates pancreatic beta-cell DNA synthesis in the presence of PDGF-BB.
Mares J, Claesson-Welsh L, Welsh M. Mares J, et al. Growth Factors. 1992;6(2):93-101. doi: 10.3109/08977199209011013. Growth Factors. 1992. PMID: 1316768
Exhibition of specific alterations in activities and mRNA levels of rat islet glycolytic and mitochondrial enzymes in three different in vitro model systems for attenuated insulin release.
Svensson C, Welsh N, Krawetz SA, Welsh M. Svensson C, et al. Diabetes. 1991 Jun;40(6):771-6. doi: 10.2337/diab.40.6.771. Diabetes. 1991. PMID: 1645683
Interleukin-1 beta increases the biosynthesis of the heat shock protein hsp70 and selectively decreases the biosynthesis of five proteins in rat pancreatic islets.
Welsh N, Welsh M, Lindquist S, Eizirik DL, Bendtzen K, Sandler S. Welsh N, et al. Autoimmunity. 1991;9(1):33-40. doi: 10.3109/08916939108997121. Autoimmunity. 1991. PMID: 1669845
Biochemical and molecular actions of interleukin-1 on pancreatic beta-cells.
Sandler S, Eizirik DL, Svensson C, Strandell E, Welsh M, Welsh N. Sandler S, et al. Autoimmunity. 1991;10(3):241-53. doi: 10.3109/08916939109001895. Autoimmunity. 1991. PMID: 1836745 Review. No abstract available.
Exposure of pancreatic islets to different alkylating agents decreases mitochondrial DNA content but only streptozotocin induces long-lasting functional impairment of B-cells.
Eizirik DL, Sandler S, Ahnström G, Welsh M. Eizirik DL, et al. Biochem Pharmacol. 1991 Nov 27;42(12):2275-82. doi: 10.1016/0006-2952(91)90230-3. Biochem Pharmacol. 1991. PMID: 1837218
GTP-binding proteins may stimulate insulin biosynthesis in rat pancreatic islets by enhancing the signal-recognition-particle-dependent translocation of the insulin mRNA poly-/mono-some complex to the endoplasmic reticulum.
Welsh N, Oberg C, Welsh M. Welsh N, et al. Biochem J. 1991 Apr 1;275 ( Pt 1)(Pt 1):23-8. doi: 10.1042/bj2750023. Biochem J. 1991. PMID: 1850238 Free PMC article.
Liposomal delivery of purified heat shock protein hsp70 into rat pancreatic islets as protection against interleukin 1 beta-induced impaired beta-cell function.
Margulis BA, Sandler S, Eizirik DL, Welsh N, Welsh M. Margulis BA, et al. Diabetes. 1991 Nov;40(11):1418-22. doi: 10.2337/diab.40.11.1418. Diabetes. 1991. PMID: 1936603
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