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Structure and function of the CFTR chloride channel.
Sheppard DN, Welsh MJ. Sheppard DN, et al. Among authors: welsh mj. Physiol Rev. 1999 Jan;79(1 Suppl):S23-45. doi: 10.1152/physrev.1999.79.1.S23. Physiol Rev. 1999. PMID: 9922375 Review.
Mutating the Conserved Q-loop Glutamine 1291 Selectively Disrupts Adenylate Kinase-dependent Channel Gating of the ATP-binding Cassette (ABC) Adenylate Kinase Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) and Reduces Channel Function in Primary Human Airway Epithelia.
Dong Q, Ernst SE, Ostedgaard LS, Shah VS, Ver Heul AR, Welsh MJ, Randak CO. Dong Q, et al. Among authors: welsh mj. J Biol Chem. 2015 May 29;290(22):14140-53. doi: 10.1074/jbc.M114.611616. Epub 2015 Apr 17. J Biol Chem. 2015. PMID: 25887396 Free PMC article.
CFTR gene transfer with AAV improves early cystic fibrosis pig phenotypes.
Steines B, Dickey DD, Bergen J, Excoffon KJ, Weinstein JR, Li X, Yan Z, Abou Alaiwa MH, Shah VS, Bouzek DC, Powers LS, Gansemer ND, Ostedgaard LS, Engelhardt JF, Stoltz DA, Welsh MJ, Sinn PL, Schaffer DV, Zabner J. Steines B, et al. Among authors: welsh mj. JCI Insight. 2016 Sep 8;1(14):e88728. doi: 10.1172/jci.insight.88728. JCI Insight. 2016. PMID: 27699238 Free PMC article.
A microRNA network regulates expression and biosynthesis of wild-type and DeltaF508 mutant cystic fibrosis transmembrane conductance regulator.
Ramachandran S, Karp PH, Jiang P, Ostedgaard LS, Walz AE, Fisher JT, Keshavjee S, Lennox KA, Jacobi AM, Rose SD, Behlke MA, Welsh MJ, Xing Y, McCray PB Jr. Ramachandran S, et al. Among authors: welsh mj. Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):13362-7. doi: 10.1073/pnas.1210906109. Epub 2012 Aug 1. Proc Natl Acad Sci U S A. 2012. PMID: 22853952 Free PMC article.
CFTR-deficient pigs display peripheral nervous system defects at birth.
Reznikov LR, Dong Q, Chen JH, Moninger TO, Park JM, Zhang Y, Du J, Hildebrand MS, Smith RJ, Randak CO, Stoltz DA, Welsh MJ. Reznikov LR, et al. Among authors: welsh mj. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):3083-8. doi: 10.1073/pnas.1222729110. Epub 2013 Feb 4. Proc Natl Acad Sci U S A. 2013. PMID: 23382208 Free PMC article.
500 results