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228 results
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Interleukin-1 beta induced activation of NF-kappa B in insulin producing RINm5F cells is prevented by the protease inhibitor N alpha-p-tosyl-L-lysine chloromethylketone.
Saldeen J, Welsh N. Saldeen J, et al. Among authors: welsh n. Biochem Biophys Res Commun. 1994 Aug 30;203(1):149-55. doi: 10.1006/bbrc.1994.2161. Biochem Biophys Res Commun. 1994. PMID: 8074648
Nitric oxide and pancreatic beta-cell destruction in insulin dependent diabetes mellitus: don't take NO for an answer.
Welsh N, Eizirik DL, Sandler S. Welsh N, et al. Autoimmunity. 1994;18(4):285-90. doi: 10.3109/08916939409009530. Autoimmunity. 1994. PMID: 7858114 Review.
The H1-receptor antagonist cetirizine protects partially against cytokine- and hydrogen peroxide-induced β-TC6 cell death in vitro.
Anvari E, Fred RG, Welsh N. Anvari E, et al. Among authors: welsh n. Pancreas. 2014 May;43(4):624-9. doi: 10.1097/MPA.0000000000000076. Pancreas. 2014. PMID: 24717804
Knock-down of ZBED6 in insulin-producing cells promotes N-cadherin junctions between beta-cells and neural crest stem cells in vitro.
Wang X, Xie B, Qi Y, Wallerman O, Vasylovska S, Andersson L, Kozlova EN, Welsh N. Wang X, et al. Among authors: welsh n. Sci Rep. 2016 Jan 11;6:19006. doi: 10.1038/srep19006. Sci Rep. 2016. PMID: 26750727 Free PMC article.
Transcription factor ZBED6 affects gene expression, proliferation, and cell death in pancreatic beta cells.
Wang X, Jiang L, Wallerman O, Engström U, Ameur A, Gupta RK, Qi Y, Andersson L, Welsh N. Wang X, et al. Among authors: welsh n. Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):15997-6002. doi: 10.1073/pnas.1303625110. Epub 2013 Sep 16. Proc Natl Acad Sci U S A. 2013. PMID: 24043816 Free PMC article.
The human insulin mRNA is partly translated via a cap- and eIF4A-independent mechanism.
Fred RG, Sandberg M, Pelletier J, Welsh N. Fred RG, et al. Among authors: welsh n. Biochem Biophys Res Commun. 2011 Sep 9;412(4):693-8. doi: 10.1016/j.bbrc.2011.08.030. Epub 2011 Aug 16. Biochem Biophys Res Commun. 2011. PMID: 21867683
The importance of RNA binding proteins in preproinsulin mRNA stability.
Fred RG, Welsh N. Fred RG, et al. Among authors: welsh n. Mol Cell Endocrinol. 2009 Jan 15;297(1-2):28-33. doi: 10.1016/j.mce.2008.06.007. Epub 2008 Jun 21. Mol Cell Endocrinol. 2009. PMID: 18621093 Review.
Role of MKK3 and p38 MAPK in cytokine-induced death of insulin-producing cells.
Makeeva N, Myers JW, Welsh N. Makeeva N, et al. Among authors: welsh n. Biochem J. 2006 Jan 1;393(Pt 1):129-39. doi: 10.1042/BJ20050814. Biochem J. 2006. PMID: 16097952 Free PMC article.
Glucose-induced binding of the polypyrimidine tract-binding protein (PTB) to the 3'-untranslated region of the insulin mRNA (ins-PRS) is inhibited by rapamycin.
Tillmar L, Welsh N. Tillmar L, et al. Among authors: welsh n. Mol Cell Biochem. 2004 May;260(1-2):85-90. doi: 10.1023/b:mcbi.0000026059.56089.e4. Mol Cell Biochem. 2004. PMID: 15228089
Cytokine-induced human islet cell death in vitro correlates with a persistently high phosphorylation of STAT-1, but not with NF-κB activation.
Hindlycke H, Lu T, Welsh N. Hindlycke H, et al. Among authors: welsh n. Biochem Biophys Res Commun. 2012 Feb 24;418(4):845-50. doi: 10.1016/j.bbrc.2012.01.130. Epub 2012 Feb 3. Biochem Biophys Res Commun. 2012. PMID: 22326919
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