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A cancer-associated polymorphism in ESCRT-III disrupts the abscission checkpoint and promotes genome instability.
Sadler JBA, Wenzel DM, Strohacker LK, Guindo-Martínez M, Alam SL, Mercader JM, Torrents D, Ullman KS, Sundquist WI, Martin-Serrano J. Sadler JBA, et al. Among authors: wenzel dm. Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):E8900-E8908. doi: 10.1073/pnas.1805504115. Epub 2018 Sep 4. Proc Natl Acad Sci U S A. 2018. PMID: 30181294 Free PMC article.
Intrinsic disorder drives N-terminal ubiquitination by Ube2w.
Vittal V, Shi L, Wenzel DM, Scaglione KM, Duncan ED, Basrur V, Elenitoba-Johnson KS, Baker D, Paulson HL, Brzovic PS, Klevit RE. Vittal V, et al. Among authors: wenzel dm. Nat Chem Biol. 2015 Jan;11(1):83-9. doi: 10.1038/nchembio.1700. Epub 2014 Dec 1. Nat Chem Biol. 2015. PMID: 25436519 Free PMC article.
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