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Intracutaneous injection of the macrophage-activating lipopeptide-2 (MALP-2) which accelerates wound healing in mice--a phase I trial in 12 patients.
Niebuhr M, Mühlradt PF, Wittmann M, Kapp A, Werfel T. Niebuhr M, et al. Among authors: werfel t. Exp Dermatol. 2008 Dec;17(12):1052-6. doi: 10.1111/j.1600-0625.2008.00750.x. Exp Dermatol. 2008. PMID: 18713273 Clinical Trial.
Allergen specificity of skin-infiltrating T cells is not restricted to a type-2 cytokine pattern in chronic skin lesions of atopic dermatitis.
Werfel T, Morita A, Grewe M, Renz H, Wahn U, Krutmann J, Kapp A. Werfel T, et al. J Invest Dermatol. 1996 Dec;107(6):871-6. doi: 10.1111/1523-1747.ep12331164. J Invest Dermatol. 1996. PMID: 8941677
Frequencies of skin-derived T cells proliferating in the presence of Dermatophagoides pteronyssinus were between one in 138 and one in 4255, indicating that only a minority of skin-infiltrating T cells are allergen specific. ...Phenotypic analysis revealed that 15% …
Frequencies of skin-derived T cells proliferating in the presence of Dermatophagoides pteronyssinus were between one in 138 and one i …
Tacalcitol ointment in the treatment of psoriasis vulgaris: a multicentre, placebo-controlled, double-blind study on efficacy and safety.
Van de Kerkhof PC, Werfel T, Haustein UF, Luger T, Czarnetzki BM, Niemann R, Plänitz-Stenzel V. Van de Kerkhof PC, et al. Among authors: werfel t. Br J Dermatol. 1996 Nov;135(5):758-65. Br J Dermatol. 1996. PMID: 8977677 Clinical Trial.
The role of circulating food antigen-specific lymphocytes in food allergic children with atopic dermatitis.
Reekers R, Beyer K, Niggemann B, Wahn U, Freihorst J, Kapp A, Werfel T. Reekers R, et al. Among authors: werfel t. Br J Dermatol. 1996 Dec;135(6):935-41. doi: 10.1046/j.1365-2133.1996.d01-1098.x. Br J Dermatol. 1996. PMID: 8977715
Twenty-eight T-cell clones (TCC) were established from the blood of three children sensitized to cow's milk and hen's egg who reacted to double-blind, placebo-controlled oral food challenge both with a deterioration of AD and with immediate symptoms. ...Our results indicat …
Twenty-eight T-cell clones (TCC) were established from the blood of three children sensitized to cow's milk and hen's egg who reacted …
Atopy patch test reactions are associated with T lymphocyte-mediated allergen-specific immune responses in atopic dermatitis.
Wistokat-Wülfing A, Schmidt P, Darsow U, Ring J, Kapp A, Werfel T. Wistokat-Wülfing A, et al. Among authors: werfel t. Clin Exp Allergy. 1999 Apr;29(4):513-21. doi: 10.1046/j.1365-2222.1999.00510.x. Clin Exp Allergy. 1999. PMID: 10202366
However, no quantitative evaluation has been performed so far comparing specific T-cell activation parameters in the peripheral blood of AD patients with positive or negative atopy patch tests (APT). ...CONCLUSION: The association of delayed skin reactions with allergen sp …
However, no quantitative evaluation has been performed so far comparing specific T-cell activation parameters in the peripheral blood …
Association of birch pollen-related food-responsive atopic dermatitis with birch pollen allergen-specific T-cell reactions.
Werfel T, Reekers R, Busche M, Schmidt P, Constien A, Wittmann M, Kapp A. Werfel T, et al. Curr Probl Dermatol. 1999;28:18-28. doi: 10.1159/000060606. Curr Probl Dermatol. 1999. PMID: 10374046 Clinical Trial. No abstract available.
What do we know about the etiopathology of the intrinsic type of atopic dermatitis?
Werfel T, Kapp A. Werfel T, et al. Curr Probl Dermatol. 1999;28:29-36. doi: 10.1159/000060597. Curr Probl Dermatol. 1999. PMID: 10374047 Review. No abstract available.
Birch pollen-related foods trigger atopic dermatitis in patients with specific cutaneous T-cell responses to birch pollen antigens.
Reekers R, Busche M, Wittmann M, Kapp A, Werfel T. Reekers R, et al. Among authors: werfel t. J Allergy Clin Immunol. 1999 Aug;104(2 Pt 1):466-72. doi: 10.1016/s0091-6749(99)70395-7. J Allergy Clin Immunol. 1999. PMID: 10452773
An enrichment of more than 25% of T-lymphocyte subpopulations defined by T-cell receptor-Vbeta elements was detected in the majority of such antigen-stimulated T-cell lines from responsive patients. A higher frequency of birch pollen-reactive T cells w …
An enrichment of more than 25% of T-lymphocyte subpopulations defined by T-cell receptor-Vbeta elements was detected in the ma …
Detection of clonal T cell receptor gamma gene rearrangements in cutaneous T cell lymphoma by LightCycler-polymerase chain reaction.
Gutzmer R, Mommert S, Kiehl P, Wittmann M, Kapp A, Werfel T. Gutzmer R, et al. Among authors: werfel t. J Invest Dermatol. 2001 Jun;116(6):926-32. doi: 10.1046/j.1523-1747.2001.01344.x. J Invest Dermatol. 2001. PMID: 11407983
Cutaneous T cell lymphoma is thought to be characterized by a monoclonal T cell infiltrate in the skin that can be detected by polymerase chain reaction-based amplification of T cell receptor gamma gene rearrangements. ...In conclusion, LightCycler--polymeras …
Cutaneous T cell lymphoma is thought to be characterized by a monoclonal T cell infiltrate in the skin that can be detected by …
Detection of anaphylatoxin receptors on CD83+ dendritic cells derived from human skin.
Kirchhoff K, Weinmann O, Zwirner J, Begemann G, Götze O, Kapp A, Werfel T. Kirchhoff K, et al. Among authors: werfel t. Immunology. 2001 Jun;103(2):210-7. doi: 10.1046/j.1365-2567.2001.01197.x. Immunology. 2001. PMID: 11412308 Free PMC article.
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