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Conference Scene: Pharmacogenomic highlights of the DGPT Annual Congress.
Werk AN, Cascorbi I. Werk AN, et al. Pharmacogenomics. 2012 Jul;13(9):997-9. doi: 10.2217/pgs.12.66. Pharmacogenomics. 2012. PMID: 22838947 No abstract available.
Highlights from the latest articles in breast cancer pharmacogenomics.
Krell J, Frampton AE, Cascorbi I, Werk A, Stebbing J. Krell J, et al. Pharmacogenomics. 2012 Apr;13(6):645-9. doi: 10.2217/pgs.12.20. Pharmacogenomics. 2012. PMID: 22515606 No abstract available.
A European Spectrum of Pharmacogenomic Biomarkers: Implications for Clinical Pharmacogenomics.
Mizzi C, Dalabira E, Kumuthini J, Dzimiri N, Balogh I, Başak N, Böhm R, Borg J, Borgiani P, Bozina N, Bruckmueller H, Burzynska B, Carracedo A, Cascorbi I, Deltas C, Dolzan V, Fenech A, Grech G, Kasiulevicius V, Kádaši Ľ, Kučinskas V, Khusnutdinova E, Loukas YL, Macek M Jr, Makukh H, Mathijssen R, Mitropoulos K, Mitropoulou C, Novelli G, Papantoni I, Pavlovic S, Saglio G, Setric J, Stojiljkovic M, Stubbs AP, Squassina A, Torres M, Turnovec M, van Schaik RH, Voskarides K, Wakil SM, Werk A, Del Zompo M, Zukic B, Katsila T, Lee MT, Motsinger-Rief A, Mc Leod HL, van der Spek PJ, Patrinos GP. Mizzi C, et al. PLoS One. 2016 Sep 16;11(9):e0162866. doi: 10.1371/journal.pone.0162866. eCollection 2016. PLoS One. 2016. PMID: 27636550 Free PMC article.
Advances and challenges in hereditary cancer pharmacogenetics.
Cascorbi I, Werk AN. Cascorbi I, et al. Among authors: werk an. Expert Opin Drug Metab Toxicol. 2017 Jan;13(1):73-82. doi: 10.1080/17425255.2017.1233965. Epub 2016 Sep 16. Expert Opin Drug Metab Toxicol. 2017. PMID: 27603572 Review.
Correction: A European Spectrum of Pharmacogenomic Biomarkers: Implications for Clinical Pharmacogenomics.
Mizzi C, Dalabira E, Kumuthini J, Dzimiri N, Balogh I, Başak N, Böhm R, Borg J, Borgiani P, Bozina N, Bruckmueller H, Burzynska B, Carracedo A, Cascorbi I, Deltas C, Dolzan V, Fenech A, Grech G, Kasiulevicius V, Kádaši Ľ, Kučinskas V, Khusnutdinova E, Loukas YL, Macek M Jr, Makukh H, Mathijssen R, Mitropoulos K, Mitropoulou C, Novelli G, Papantoni I, Pavlovic S, Saglio G, Sertić J, Stojiljkovic M, Stubbs AP, Squassina A, Torres M, Turnovec M, van Schaik RH, Voskarides K, Wakil SM, Werk A, Del Zompo M, Zukic B, Katsila T, Lee MT, Motsinger-Rief A, Mc Leod HL, van der Spek PJ, Patrinos GP. Mizzi C, et al. PLoS One. 2017 Feb 16;12(2):e0172595. doi: 10.1371/journal.pone.0172595. eCollection 2017. PLoS One. 2017. PMID: 28207884 Free PMC article.
Functional gene variants of CYP3A4.
Werk AN, Cascorbi I. Werk AN, et al. Clin Pharmacol Ther. 2014 Sep;96(3):340-8. doi: 10.1038/clpt.2014.129. Epub 2014 Jun 13. Clin Pharmacol Ther. 2014. PMID: 24926778 Review.
Which Genetic Determinants Should be Considered for Tacrolimus Dose Optimization in Kidney Transplantation? A Combined Analysis of Genes Affecting the CYP3A Locus.
Bruckmueller H, Werk AN, Renders L, Feldkamp T, Tepel M, Borst C, Caliebe A, Kunzendorf U, Cascorbi I. Bruckmueller H, et al. Among authors: werk an. Ther Drug Monit. 2015 Jun;37(3):288-95. doi: 10.1097/FTD.0000000000000142. Ther Drug Monit. 2015. PMID: 25271728
Identification and characterization of a defective CYP3A4 genotype in a kidney transplant patient with severely diminished tacrolimus clearance.
Werk AN, Lefeldt S, Bruckmueller H, Hemmrich-Stanisak G, Franke A, Roos M, Küchle C, Steubl D, Schmaderer C, Bräsen JH, Heemann U, Cascorbi I, Renders L. Werk AN, et al. Clin Pharmacol Ther. 2014 Apr;95(4):416-22. doi: 10.1038/clpt.2013.210. Epub 2013 Oct 14. Clin Pharmacol Ther. 2014. PMID: 24126681
Challenges in pharmacogenetics.
Cascorbi I, Bruhn O, Werk AN. Cascorbi I, et al. Among authors: werk an. Eur J Clin Pharmacol. 2013 May;69 Suppl 1:17-23. doi: 10.1007/s00228-013-1492-x. Epub 2013 May 3. Eur J Clin Pharmacol. 2013. PMID: 23640184 Review.
Genetic variants may play an important role in mRNA-miRNA interaction: evidence for haplotype-dependent downregulation of ABCC2 (MRP2) by miRNA-379.
Werk AN, Bruckmueller H, Haenisch S, Cascorbi I. Werk AN, et al. Pharmacogenet Genomics. 2014 Jun;24(6):283-91. doi: 10.1097/FPC.0000000000000046. Pharmacogenet Genomics. 2014. PMID: 24743544
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