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Opposing effects of IL-1 alpha and IL-1 beta on malignancy patterns. Tumor cell-associated IL-1 alpha potentiates anti-tumor immune responses and tumor regression, whereas IL-1 beta potentiates invasiveness.
Apte RN, Dvorkin T, Song X, Fima E, Krelin Y, Yulevitch A, Gurfinkel R, Werman A, White RM, Argov S, Shendler Y, Bjorkdahl O, Dohlsten M, Zoller M, Segal S, Voronov E. Apte RN, et al. Among authors: werman a. Adv Exp Med Biol. 2000;479:277-88. Adv Exp Med Biol. 2000. PMID: 10897428 Review. No abstract available.