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205 results
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Characterization of beta-adrenoceptor antagonists as substrates and inhibitors of the drug transporter P-glycoprotein.
Bachmakov I, Werner U, Endress B, Auge D, Fromm MF. Bachmakov I, et al. Among authors: werner u. Fundam Clin Pharmacol. 2006 Jun;20(3):273-82. doi: 10.1111/j.1472-8206.2006.00408.x. Fundam Clin Pharmacol. 2006. PMID: 16671962
Effect of selective cyclooxygenase-2 inhibitors on heart rate in healthy young men.
Lamprecht C, Werner U, Werner D, Schaefer S, Renner B, Fromm M, Brune K. Lamprecht C, et al. Among authors: werner u, werner d. Am J Cardiol. 2005 Jun 15;95(12):1531-2. doi: 10.1016/j.amjcard.2005.02.033. Am J Cardiol. 2005. PMID: 15950593
Bioavailability of diclofenac potassium at low doses.
Hinz B, Chevts J, Renner B, Wuttke H, Rau T, Schmidt A, Szelenyi I, Brune K, Werner U. Hinz B, et al. Among authors: werner u. Br J Clin Pharmacol. 2005 Jan;59(1):80-4. doi: 10.1111/j.1365-2125.2005.02226.x. Br J Clin Pharmacol. 2005. PMID: 15606444 Free PMC article. Clinical Trial.
Aceclofenac spares cyclooxygenase 1 as a result of limited but sustained biotransformation to diclofenac.
Hinz B, Rau T, Auge D, Werner U, Ramer R, Rietbrock S, Brune K. Hinz B, et al. Among authors: werner u. Clin Pharmacol Ther. 2003 Sep;74(3):222-35. doi: 10.1016/S0009-9236(03)00167-X. Clin Pharmacol Ther. 2003. PMID: 12966366 Clinical Trial.
Celecoxib inhibits metabolism of cytochrome P450 2D6 substrate metoprolol in humans.
Werner U, Werner D, Rau T, Fromm MF, Hinz B, Brune K. Werner U, et al. Among authors: werner d. Clin Pharmacol Ther. 2003 Aug;74(2):130-7. doi: 10.1016/S0009-9236(03)00120-6. Clin Pharmacol Ther. 2003. PMID: 12891223 Clinical Trial.
Caffeine accelerates absorption and enhances the analgesic effect of acetaminophen.
Renner B, Clarke G, Grattan T, Beisel A, Mueller C, Werner U, Kobal G, Brune K. Renner B, et al. Among authors: werner u. J Clin Pharmacol. 2007 Jun;47(6):715-26. doi: 10.1177/0091270007299762. Epub 2007 Apr 18. J Clin Pharmacol. 2007. PMID: 17442681 Clinical Trial.
Gender is an important determinant of the disposition of the loop diuretic torasemide.
Werner U, Werner D, Heinbüchner S, Graf B, Ince H, Kische S, Thürmann P, König J, Fromm MF, Zolk O. Werner U, et al. Among authors: werner d. J Clin Pharmacol. 2010 Feb;50(2):160-8. doi: 10.1177/0091270009337514. Epub 2009 Nov 23. J Clin Pharmacol. 2010. PMID: 19934028 Clinical Trial.
Impact of the CYP2D6 genotype on the clinical effects of metoprolol: a prospective longitudinal study.
Rau T, Wuttke H, Michels LM, Werner U, Bergmann K, Kreft M, Fromm MF, Eschenhagen T. Rau T, et al. Among authors: werner u. Clin Pharmacol Ther. 2009 Mar;85(3):269-72. doi: 10.1038/clpt.2008.218. Epub 2008 Nov 26. Clin Pharmacol Ther. 2009. PMID: 19037197
Valdecoxib does not interfere with the CYP2D6 substrate metoprolol.
Werner U, Lamprecht C, Werner D, Schaefer S, Wuttke H, Hinz B, Fromm MF, Brune K. Werner U, et al. Among authors: werner d. Int J Clin Pharmacol Ther. 2006 Sep;44(9):397-400. doi: 10.5414/cpp44397. Int J Clin Pharmacol Ther. 2006. PMID: 16995327 Clinical Trial.
Pharmacokinetics of mezlocillin and sulbactam under continuous veno-venous hemodialysis (CVVHD) in intensive care patients with acute renal failure.
Rohde B, Werner U, Hickstein H, Ehmcke H, Drewelow B. Rohde B, et al. Among authors: werner u. Eur J Clin Pharmacol. 1997;53(2):111-5. doi: 10.1007/s002280050347. Eur J Clin Pharmacol. 1997. PMID: 9403281 Clinical Trial.
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