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Surgical adhesions in mice are derived from mesothelial cells and can be targeted by antibodies against mesothelial markers.
Tsai JM, Sinha R, Seita J, Fernhoff N, Christ S, Koopmans T, Krampitz GW, McKenna KM, Xing L, Sandholzer M, Sales JH, Shoham M, McCracken M, Joubert LM, Gordon SR, Poux N, Wernig G, Norton JA, Weissman IL, Rinkevich Y. Tsai JM, et al. Among authors: wernig g. Sci Transl Med. 2018 Nov 28;10(469):eaan6735. doi: 10.1126/scitranslmed.aan6735. Sci Transl Med. 2018. PMID: 30487249
Selective hematopoietic stem cell ablation using CD117-antibody-drug-conjugates enables safe and effective transplantation with immunity preservation.
Czechowicz A, Palchaudhuri R, Scheck A, Hu Y, Hoggatt J, Saez B, Pang WW, Mansour MK, Tate TA, Chan YY, Walck E, Wernig G, Shizuru JA, Winau F, Scadden DT, Rossi DJ. Czechowicz A, et al. Among authors: wernig g. Nat Commun. 2019 Feb 6;10(1):617. doi: 10.1038/s41467-018-08201-x. Nat Commun. 2019. PMID: 30728354 Free PMC article.
Mapping the Pairwise Choices Leading from Pluripotency to Human Bone, Heart, and Other Mesoderm Cell Types.
Loh KM, Chen A, Koh PW, Deng TZ, Sinha R, Tsai JM, Barkal AA, Shen KY, Jain R, Morganti RM, Shyh-Chang N, Fernhoff NB, George BM, Wernig G, Salomon REA, Chen Z, Vogel H, Epstein JA, Kundaje A, Talbot WS, Beachy PA, Ang LT, Weissman IL. Loh KM, et al. Among authors: wernig g. Cell. 2016 Jul 14;166(2):451-467. doi: 10.1016/j.cell.2016.06.011. Cell. 2016. PMID: 27419872 Free PMC article.
Tuning cytokine receptor signaling by re-orienting dimer geometry with surrogate ligands.
Moraga I, Wernig G, Wilmes S, Gryshkova V, Richter CP, Hong WJ, Sinha R, Guo F, Fabionar H, Wehrman TS, Krutzik P, Demharter S, Plo I, Weissman IL, Minary P, Majeti R, Constantinescu SN, Piehler J, Garcia KC. Moraga I, et al. Among authors: wernig g. Cell. 2015 Mar 12;160(6):1196-208. doi: 10.1016/j.cell.2015.02.011. Epub 2015 Feb 26. Cell. 2015. PMID: 25728669 Free PMC article.
Unifying mechanism for different fibrotic diseases.
Wernig G, Chen SY, Cui L, Van Neste C, Tsai JM, Kambham N, Vogel H, Natkunam Y, Gilliland DG, Nolan G, Weissman IL. Wernig G, et al. Proc Natl Acad Sci U S A. 2017 May 2;114(18):4757-4762. doi: 10.1073/pnas.1621375114. Epub 2017 Apr 19. Proc Natl Acad Sci U S A. 2017. PMID: 28424250 Free PMC article.
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