West AP - Search Results

1

Mitochondrial DNA in innate immune responses and inflammatory pathology.

West AP, Shadel GS. West AP, et al. Nat Rev Immunol. 2017 Jun;17(6):363-375. doi: 10.1038/nri.2017.21. Epub 2017 Apr 10. Nat Rev Immunol. 2017. PMID: 28393922 Free PMC article. Review.

2

NF-kappaB and the immune response.

Hayden MS, West AP, Ghosh S. Hayden MS, et al. Among authors: west ap. Oncogene. 2006 Oct 30;25(51):6758-80. doi: 10.1038/sj.onc.1209943. Oncogene. 2006. PMID: 17072327 Review.

3

Subversion of innate immune responses by Brucella through the targeted degradation of the TLR signaling adapter, MAL.

Sengupta D, Koblansky A, Gaines J, Brown T, West AP, Zhang D, Nishikawa T, Park SG, Roop RM 2nd, Ghosh S. Sengupta D, et al. Among authors: west ap. J Immunol. 2010 Jan 15;184(2):956-64. doi: 10.4049/jimmunol.0902008. Epub 2009 Dec 14. J Immunol. 2010. PMID: 20018612 Free PMC article.

4

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS.

West AP, Brodsky IE, Rahner C, Woo DK, Erdjument-Bromage H, Tempst P, Walsh MC, Choi Y, Shadel GS, Ghosh S. West AP, et al. Nature. 2011 Apr 28;472(7344):476-80. doi: 10.1038/nature09973. Nature. 2011. PMID: 21525932 Free PMC article.

5

Mitochondria in innate immune responses.

West AP, Shadel GS, Ghosh S. West AP, et al. Nat Rev Immunol. 2011 Jun;11(6):389-402. doi: 10.1038/nri2975. Epub 2011 May 20. Nat Rev Immunol. 2011. PMID: 21597473 Free PMC article. Review.

6

Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA.

Rongvaux A, Jackson R, Harman CC, Li T, West AP, de Zoete MR, Wu Y, Yordy B, Lakhani SA, Kuan CY, Taniguchi T, Shadel GS, Chen ZJ, Iwasaki A, Flavell RA. Rongvaux A, et al. Among authors: west ap. Cell. 2014 Dec 18;159(7):1563-77. doi: 10.1016/j.cell.2014.11.037. Cell. 2014. PMID: 25525875 Free PMC article.

7

Aging-dependent alterations in gene expression and a mitochondrial signature of responsiveness to human influenza vaccination.

Thakar J, Mohanty S, West AP, Joshi SR, Ueda I, Wilson J, Meng H, Blevins TP, Tsang S, Trentalange M, Siconolfi B, Park K, Gill TM, Belshe RB, Kaech SM, Shadel GS, Kleinstein SH, Shaw AC. Thakar J, et al. Among authors: west ap. Aging (Albany NY). 2015 Jan;7(1):38-52. doi: 10.18632/aging.100720. Aging (Albany NY). 2015. PMID: 25596819 Free PMC article.

8

Mitochondrial DNA stress primes the antiviral innate immune response.

West AP, Khoury-Hanold W, Staron M, Tal MC, Pineda CM, Lang SM, Bestwick M, Duguay BA, Raimundo N, MacDuff DA, Kaech SM, Smiley JR, Means RE, Iwasaki A, Shadel GS. West AP, et al. Nature. 2015 Apr 23;520(7548):553-7. doi: 10.1038/nature14156. Epub 2015 Feb 2. Nature. 2015. PMID: 25642965 Free PMC article.

9

Mitochondrial dysfunction as a trigger of innate immune responses and inflammation.

West AP. West AP. Toxicology. 2017 Nov 1;391:54-63. doi: 10.1016/j.tox.2017.07.016. Epub 2017 Jul 29. Toxicology. 2017. PMID: 28765055 Review.

10

Mitochondrial DNA Stress Signalling Protects the Nuclear Genome.

Wu Z, Oeck S, West AP, Mangalhara KC, Sainz AG, Newman LE, Zhang XO, Wu L, Yan Q, Bosenberg M, Liu Y, Sulkowski PL, Tripple V, Kaech SM, Glazer PM, Shadel GS. Wu Z, et al. Among authors: west ap. Nat Metab. 2019 Dec;1(12):1209-1218. doi: 10.1038/s42255-019-0150-8. Epub 2019 Dec 9. Nat Metab. 2019. PMID: 32395698 Free PMC article.

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