West AP - Search Results

1

Mitochondrial dysfunction as a trigger of innate immune responses and inflammation.

West AP. West AP. Toxicology. 2017 Nov 1;391:54-63. doi: 10.1016/j.tox.2017.07.016. Epub 2017 Jul 29. Toxicology. 2017. PMID: 28765055 Review.

2

Mitochondrial DNA in innate immune responses and inflammatory pathology.

West AP, Shadel GS. West AP, et al. Nat Rev Immunol. 2017 Jun;17(6):363-375. doi: 10.1038/nri.2017.21. Epub 2017 Apr 10. Nat Rev Immunol. 2017. PMID: 28393922 Free PMC article. Review.

3

Impact of pharmacological agents on mitochondrial function: a growing opportunity?

Stoker ML, Newport E, Hulit JC, West AP, Morten KJ. Stoker ML, et al. Among authors: west ap. Biochem Soc Trans. 2019 Dec 20;47(6):1757-1772. doi: 10.1042/BST20190280. Biochem Soc Trans. 2019. PMID: 31696924 Free PMC article. Review.

4

Elevated type I interferon responses potentiate metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice.

Lei Y, Guerra Martinez C, Torres-Odio S, Bell SL, Birdwell CE, Bryant JD, Tong CW, Watson RO, West LC, West AP. Lei Y, et al. Among authors: west lc, west ap. Sci Adv. 2021 May 26;7(22):eabe7548. doi: 10.1126/sciadv.abe7548. Print 2021 May. Sci Adv. 2021. PMID: 34039599 Free PMC article.

5

Increased presence of nuclear DNAJA3 and upregulation of cytosolic STAT1 and of nucleic acid sensors trigger innate immunity in the ClpP-null mouse.

Maletzko A, Key J, Wittig I, Gispert S, Koepf G, Canet-Pons J, Torres-Odio S, West AP, Auburger G. Maletzko A, et al. Among authors: west ap. Neurogenetics. 2021 Oct;22(4):297-312. doi: 10.1007/s10048-021-00657-2. Epub 2021 Aug 3. Neurogenetics. 2021. PMID: 34345994 Free PMC article.

6

Assessing Mitochondrial DNA Release into the Cytosol and Subsequent Activation of Innate Immune-related Pathways in Mammalian Cells.

Bryant JD, Lei Y, VanPortfliet JJ, Winters AD, West AP. Bryant JD, et al. Among authors: west ap. Curr Protoc. 2022 Feb;2(2):e372. doi: 10.1002/cpz1.372. Curr Protoc. 2022. PMID: 35175686 Free PMC article.

7

Mitochondrial DNA release and sensing in innate immune responses.

VanPortfliet JJ, Chute C, Lei Y, Shutt TE, West AP. VanPortfliet JJ, et al. Among authors: west ap. Hum Mol Genet. 2024 May 22;33(R1):R80-R91. doi: 10.1093/hmg/ddae031. Hum Mol Genet. 2024. PMID: 38779772 Review.

8

Mitochondria in innate immune responses.

West AP, Shadel GS, Ghosh S. West AP, et al. Nat Rev Immunol. 2011 Jun;11(6):389-402. doi: 10.1038/nri2975. Epub 2011 May 20. Nat Rev Immunol. 2011. PMID: 21597473 Free PMC article. Review.

9

Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA.

Rongvaux A, Jackson R, Harman CC, Li T, West AP, de Zoete MR, Wu Y, Yordy B, Lakhani SA, Kuan CY, Taniguchi T, Shadel GS, Chen ZJ, Iwasaki A, Flavell RA. Rongvaux A, et al. Among authors: west ap. Cell. 2014 Dec 18;159(7):1563-77. doi: 10.1016/j.cell.2014.11.037. Cell. 2014. PMID: 25525875 Free PMC article.

10

Editorial.

West AP. West AP. Mitochondrion. 2018 Jul;41:1. doi: 10.1016/j.mito.2018.05.002. Mitochondrion. 2018. PMID: 29887010 No abstract available.

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