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Loss of mitochondrial ClpP, Lonp1, and Tfam triggers transcriptional induction of Rnf213, a susceptibility factor for moyamoya disease.
Key J, Maletzko A, Kohli A, Gispert S, Torres-Odio S, Wittig I, Heidler J, Bárcena C, López-Otín C, Lei Y, West AP, Münch C, Auburger G. Key J, et al. Among authors: west ap. Neurogenetics. 2020 Jul;21(3):187-203. doi: 10.1007/s10048-020-00609-2. Epub 2020 Apr 28. Neurogenetics. 2020. PMID: 32342250 Free PMC article.
A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1.
Zhao B, Du F, Xu P, Shu C, Sankaran B, Bell SL, Liu M, Lei Y, Gao X, Fu X, Zhu F, Liu Y, Laganowsky A, Zheng X, Ji JY, West AP, Watson RO, Li P. Zhao B, et al. Among authors: west ap. Nature. 2019 May;569(7758):718-722. doi: 10.1038/s41586-019-1228-x. Epub 2019 May 22. Nature. 2019. PMID: 31118511 Free PMC article.
Impaired lysosomal acidification triggers iron deficiency and inflammation in vivo.
Yambire KF, Rostosky C, Watanabe T, Pacheu-Grau D, Torres-Odio S, Sanchez-Guerrero A, Senderovich O, Meyron-Holtz EG, Milosevic I, Frahm J, West AP, Raimundo N. Yambire KF, et al. Among authors: west ap. Elife. 2019 Dec 3;8:e51031. doi: 10.7554/eLife.51031. Elife. 2019. PMID: 31793879 Free PMC article.
188 results