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Activated microglia drive demyelination via CSF1R signaling.
Marzan DE, Brügger-Verdon V, West BL, Liddelow S, Samanta J, Salzer JL. Marzan DE, et al. Glia. 2021 Jun;69(6):1583-1604. doi: 10.1002/glia.23980. Epub 2021 Feb 23. Glia. 2021. PMID: 33620118 Free PMC article.
Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model.
Spangenberg E, Severson PL, Hohsfield LA, Crapser J, Zhang J, Burton EA, Zhang Y, Spevak W, Lin J, Phan NY, Habets G, Rymar A, Tsang G, Walters J, Nespi M, Singh P, Broome S, Ibrahim P, Zhang C, Bollag G, West BL, Green KN. Spangenberg E, et al. Nat Commun. 2019 Aug 21;10(1):3758. doi: 10.1038/s41467-019-11674-z. Nat Commun. 2019. PMID: 31434879 Free PMC article.
992 results