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Biology of the prion gene complex.
Mastrangelo P, Westaway D. Mastrangelo P, et al. Among authors: westaway d. Biochem Cell Biol. 2001;79(5):613-28. doi: 10.1139/o01-142. Biochem Cell Biol. 2001. PMID: 11716303 Review.
Genetic mapping of activity determinants within cellular prion proteins: N-terminal modules in PrPC offset pro-apoptotic activity of the Doppel helix B/B' region.
Drisaldi B, Coomaraswamy J, Mastrangelo P, Strome B, Yang J, Watts JC, Chishti MA, Marvi M, Windl O, Ahrens R, Major F, Sy MS, Kretzschmar H, Fraser PE, Mount HT, Westaway D. Drisaldi B, et al. Among authors: westaway d. J Biol Chem. 2004 Dec 31;279(53):55443-54. doi: 10.1074/jbc.M404794200. Epub 2004 Sep 29. J Biol Chem. 2004. PMID: 15459186 Free article.
The expanding universe of prion diseases.
Watts JC, Balachandran A, Westaway D. Watts JC, et al. Among authors: westaway d. PLoS Pathog. 2006 Mar;2(3):e26. doi: 10.1371/journal.ppat.0020026. PLoS Pathog. 2006. PMID: 16609731 Free PMC article. Review.
TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity.
Chen F, Hasegawa H, Schmitt-Ulms G, Kawarai T, Bohm C, Katayama T, Gu Y, Sanjo N, Glista M, Rogaeva E, Wakutani Y, Pardossi-Piquard R, Ruan X, Tandon A, Checler F, Marambaud P, Hansen K, Westaway D, St George-Hyslop P, Fraser P. Chen F, et al. Among authors: westaway d. Nature. 2006 Apr 27;440(7088):1208-12. doi: 10.1038/nature04667. Nature. 2006. PMID: 16641999
The CNS glycoprotein Shadoo has PrP(C)-like protective properties and displays reduced levels in prion infections.
Watts JC, Drisaldi B, Ng V, Yang J, Strome B, Horne P, Sy MS, Yoong L, Young R, Mastrangelo P, Bergeron C, Fraser PE, Carlson GA, Mount HT, Schmitt-Ulms G, Westaway D. Watts JC, et al. Among authors: westaway d. EMBO J. 2007 Sep 5;26(17):4038-50. doi: 10.1038/sj.emboj.7601830. Epub 2007 Aug 16. EMBO J. 2007. PMID: 17703189 Free PMC article.
221 results