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Cell-cycle signaling: Atm displays its many talents.
Westphal CH. Westphal CH. Curr Biol. 1997 Dec 1;7(12):R789-92. doi: 10.1016/s0960-9822(06)00406-4. Curr Biol. 1997. PMID: 9382823 Review.
The mammalian mid-pachytene checkpoint: meiotic arrest in spermatocytes with a mutation in Atm alone or in combination with a Trp53 (p53) or Cdkn1a (p21/cip1) mutation.
Ashley T, Westphal C, Plug-de Maggio A, de Rooij DG. Ashley T, et al. Cytogenet Genome Res. 2004;107(3-4):256-62. doi: 10.1159/000080603. Cytogenet Genome Res. 2004. PMID: 15467370
Loss of atm radiosensitizes multiple p53 null tissues.
Westphal CH, Hoyes KP, Canman CE, Huang X, Kastan MB, Hendry JH, Leder P. Westphal CH, et al. Cancer Res. 1998 Dec 15;58(24):5637-9. Cancer Res. 1998. PMID: 9865712
Westphal et al., Nat. Genet., 16: 397-401, 1997) to be independent of p53. Expanding on previous work, we have looked at in vivo bone marrow resistance in p53-deficient mice. ...
Westphal et al., Nat. Genet., 16: 397-401, 1997) to be independent of p53. Expanding on previous work, we have looked at in vivo bone
Atm-dependent interactions of a mammalian chk1 homolog with meiotic chromosomes.
Flaggs G, Plug AW, Dunks KM, Mundt KE, Ford JC, Quiggle MR, Taylor EM, Westphal CH, Ashley T, Hoekstra MF, Carr AM. Flaggs G, et al. Curr Biol. 1997 Dec 1;7(12):977-86. doi: 10.1016/s0960-9822(06)00417-9. Curr Biol. 1997. PMID: 9382850
Atm inactivation results in aberrant telomere clustering during meiotic prophase.
Pandita TK, Westphal CH, Anger M, Sawant SG, Geard CR, Pandita RK, Scherthan H. Pandita TK, et al. Mol Cell Biol. 1999 Jul;19(7):5096-105. doi: 10.1128/mcb.19.7.5096. Mol Cell Biol. 1999. PMID: 10373558 Free PMC article.
Ataxia telangiectasia mutated expression and activation in the testis.
Hamer G, Kal HB, Westphal CH, Ashley T, de Rooij DG. Hamer G, et al. Biol Reprod. 2004 Apr;70(4):1206-12. doi: 10.1095/biolreprod.103.024950. Epub 2003 Dec 17. Biol Reprod. 2004. PMID: 14681204
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes.
Milne JC, Lambert PD, Schenk S, Carney DP, Smith JJ, Gagne DJ, Jin L, Boss O, Perni RB, Vu CB, Bemis JE, Xie R, Disch JS, Ng PY, Nunes JJ, Lynch AV, Yang H, Galonek H, Israelian K, Choy W, Iffland A, Lavu S, Medvedik O, Sinclair DA, Olefsky JM, Jirousek MR, Elliott PJ, Westphal CH. Milne JC, et al. Among authors: westphal ch. Nature. 2007 Nov 29;450(7170):712-6. doi: 10.1038/nature06261. Nature. 2007. PMID: 18046409 Free PMC article.
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