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Enzymes and receptors in the leukotriene cascade.
Haeggström JZ, Wetterholm A. Haeggström JZ, et al. Among authors: wetterholm a. Cell Mol Life Sci. 2002 May;59(5):742-53. doi: 10.1007/s00018-002-8463-1. Cell Mol Life Sci. 2002. PMID: 12088275 Review.
Phosphorylation of Leukotriene C4 Synthase at Serine 36 Impairs Catalytic Activity.
Ahmad S, Ytterberg AJ, Thulasingam M, Tholander F, Bergman T, Zubarev R, Wetterholm A, Rinaldo-Matthis A, Haeggström JZ. Ahmad S, et al. Among authors: wetterholm a. J Biol Chem. 2016 Aug 26;291(35):18410-8. doi: 10.1074/jbc.M116.735647. Epub 2016 Jun 30. J Biol Chem. 2016. PMID: 27365393 Free PMC article.
Arginine 104 is a key catalytic residue in leukotriene C4 synthase.
Rinaldo-Matthis A, Wetterholm A, Martinez Molina D, Holm J, Niegowski D, Ohlson E, Nordlund P, Morgenstern R, Haeggström JZ. Rinaldo-Matthis A, et al. Among authors: wetterholm a. J Biol Chem. 2010 Dec 24;285(52):40771-6. doi: 10.1074/jbc.M110.105940. Epub 2010 Oct 27. J Biol Chem. 2010. PMID: 20980252 Free PMC article.
Advances in eicosanoid research, novel therapeutic implications.
Haeggström JZ, Rinaldo-Matthis A, Wheelock CE, Wetterholm A. Haeggström JZ, et al. Among authors: wetterholm a. Biochem Biophys Res Commun. 2010 May 21;396(1):135-9. doi: 10.1016/j.bbrc.2010.03.140. Biochem Biophys Res Commun. 2010. PMID: 20494126 Review.
Structure and catalytic mechanisms of leukotriene A4 hydrolase.
Haeggström JZ, Tholander F, Wetterholm A. Haeggström JZ, et al. Among authors: wetterholm a. Prostaglandins Other Lipid Mediat. 2007 May;83(3):198-202. doi: 10.1016/j.prostaglandins.2007.01.006. Epub 2007 Jan 17. Prostaglandins Other Lipid Mediat. 2007. PMID: 17481555 Review.
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